5874-97-5 Usage
Description
Orciprenaline sulfate, also known as Alupent or Prometa, is a synthetically derived medication that belongs to the class of beta-adrenergic agonists. It is a white or almost white, slightly hygroscopic, crystalline powder. This medication primarily functions as a bronchodilator, which aids in relaxing the muscles in the airways and improving breathing for patients with respiratory conditions.
Uses
Orciprenaline sulfate is used as a bronchodilator for the treatment of various respiratory conditions, such as asthma and chronic obstructive pulmonary disease (COPD). It works by stimulating the beta2-adrenoceptors in the lungs, leading to the relaxation of bronchial smooth muscles and dilation of the airways. This helps to alleviate symptoms like shortness of breath, wheezing, and coughing.
Used in Pharmaceutical Industry:
Orciprenaline sulfate is used as a beta2-adrenoceptor agonist for the development of medications aimed at treating respiratory disorders. Its bronchodilating properties make it a valuable component in the formulation of drugs that target conditions like asthma and COPD, providing relief and improved lung function for patients.
Additionally, it may be used in combination with other medications to enhance their bronchodilating effects or to manage specific symptoms in patients with respiratory conditions. The pharmaceutical industry utilizes orciprenaline sulfate to create effective treatments that can significantly improve the quality of life for individuals suffering from respiratory issues.
Therapeutic Function
Bronchodilator
Pharmacokinetics
Metaproterenol is a direct-acting resorcinol analogue of isoproterenol. The N-isopropyl is
β-directing, and the combination with the resorcinol ring system enhances the selectivity for the
β2-receptors. It is the least potent of the β2-selective agonists, however, most likely because of
the poor β2-selectivity of the isopropyl group. It has good oral bioavailability being resistant to
COMT and only slowly metabolized by MAO. When administered orally, it has an onset of
approximately 30 minutes with a 4-hour duration. Inhaled metaproterenol can have an onset as
quick as 5 minutes; however, it can be as long as 30 minutes in susceptible individuals.
Metaproterenol is available in tablet, syrup, and inhalation dosage forms and is recommended for
bronchial asthma attacks and treatment of acute asthmatic attacks in children 6 years of age and
older (5% solution for inhalation only). Metaproterenol has the same adverse effect profile as
other adrenergic agonists, but with a decreased incidence of arrhythmias.
Check Digit Verification of cas no
The CAS Registry Mumber 5874-97-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,8,7 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5874-97:
(6*5)+(5*8)+(4*7)+(3*4)+(2*9)+(1*7)=135
135 % 10 = 5
So 5874-97-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO3.H2O4S/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8;1-5(2,3)4/h3-5,7,11-15H,6H2,1-2H3;(H2,1,2,3,4)