5876-17-5 Usage
Description
4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol is a Haplophyllum alkaloid derived from the plants H. perforatum (MB) Kar. et Kir. and H. robustum Bge. It is characterized by its crystalline hydrochloride form, with a melting point of 168-9°C. This alkaloid can be isomerized to isohaplopine, which forms colorless rods from MeOH with a melting point of 170-2°C.
Uses
Used in Pharmaceutical Industry:
4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol is used as a pharmaceutical compound for its potential therapeutic properties. Its alkaloid nature and unique structure make it a candidate for further research and development in the field of medicine.
Used in Chemical Research:
4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol is also used as a subject of study in chemical research, particularly in the investigation of alkaloid structures, their properties, and potential applications in various fields.
References
Sidyakin, Yunusov, Dokl. Akad. Nauk. Uzbek SSR, 4, 39 (1962)
Fakhritdinova, Sidyakin, Yunusov,Khim.Prir. Soedin., 1, 107 (1965)
Check Digit Verification of cas no
The CAS Registry Mumber 5876-17-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,8,7 and 6 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5876-17:
(6*5)+(5*8)+(4*7)+(3*6)+(2*1)+(1*7)=125
125 % 10 = 5
So 5876-17-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H11NO4/c1-16-11-7-3-4-9(15)12(17-2)10(7)14-13-8(11)5-6-18-13/h3-6,14H,1-2H3
5876-17-5Relevant articles and documents
Biphenyl dioxygenase-catalysed cis-dihydroxylation of tricyclic azaarenes: Chemoenzymatic synthesis of arene oxide metabolites and furoquinoline alkaloids
Boyd, Derek R.,Sharma, Narain D.,Carroll, Jonathan G.,Loke, Pui L.,O'Dowd, Colin R.,Allen, Christopher C. R.
, p. 10944 - 10955 (2013/09/02)
Biotransformation of acridine, dictamnine and 4-chlorofuro[2,3-b]quinolone, using whole cells of Sphingomonas yanoikuyae B8/36, yielded five enantiopure cyclic cis-dihydrodiols, from biphenyl dioxygenase-catalysed dihydroxylation of the carbocyclic rings.
STRUCTURE OF HAPLOSIDINE
Rasulova, Kh. A.,Bessonova, I. A.,Yagudaev, M. R.,Yunusov, S. Yu.
, p. 82 - 84 (2007/10/02)
A new glycoalkaloid, haplosidine, has been isolated from the epigeal part of the plant Haplophyllum perforatum, and its structure has been established as 7- 3)-2'-O-acetyl-α-L-rhamnopyranosyloxy>-4,8-dimethoxyfuranoquinoline.
ALKALOIDS OF THE ROOTS OF THE Haplophyllum obtusifolium
Bessonova, I. A.,Yunusov, S. Yu.
, p. 684 - 686 (2007/10/02)
The roots of the Haplophyllum obtusifolium Lebed. have been yielded robustine, dictamnine, skimmianine, γ-fagarine, and evoxine and the new alkaloid haplobine for which on the basis of spectral characteristics and a passage to the main alkaloid haplopine (7-hydroxy-4,8-dimethoxylfuranoquinoline) the structure of 7-(3'-chloromethylbut-2'-enyloxy)-4,8-dimethoxyfuranoquinoline has been established.