587869-81-6

Basic information

• Product Name: 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E,3S)-3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1-octe nyl]hexahydro-, (3aR,4R,5R,6aS)-
• Synonyms: 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E,3S)-3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1-octe nyl]hexahydro-, (3aR,4R,5R,6aS)-;(3AR,4R,5R,6aS)-4-((S,E)-3-((tert-Butyldimethylsilyl)oxy)oct-1-en-1-yl)-2-oxohexahydro-2H-cyclope;2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E,3S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-octen-1-yl]hexahydro-, (3aR,4R,5R,6aS)-;(3AR,4R,5R,6aS)-4-((S,E)-3-((tert-Butyldimethylsilyl)oxy)oct-1-en-1-yl)-2-oxohexahydro-2H-cycl;(3aR,4R,5R,6aS)-4-((S,E)-3-((tert-Butyldimethylsilyl)oxy)oct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
• CAS NO: 587869-81-6
• Molecular Formula: C₂₈H₄₂O₅Si
• Molecular Weight: 486.71558
• Mol File: 587869-81-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E,3S)-3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1-octe nyl]hexahydro-, (3aR,4R,5R,6aS)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E,3S)-3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1-octe nyl]hexahydro-, (3aR,4R,5R,6aS)-(587869-81-6)
• EPA Substance Registry System: 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E,3S)-3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1-octe nyl]hexahydro-, (3aR,4R,5R,6aS)-(587869-81-6)

Safety Data

• Hazardous Substances Data: 587869-81-6(Hazardous Substances Data)

Usage

General Description

2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E,3S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-octenyl]hexahydro-, (3aR,4R,5R,6aS)- is a complex chemical compound. Its molecular structure encompasses a variety of functional groups, including a cyclopentafuranone ring, a benzoyloxy group, a dimethylsilyl group, and an octenyl chain. The prefixes (1E,3S) and (3aR,4R,5R,6aS) denote the configuration and orientation of the constituent atoms in the molecule, indicating its stereochemistry. It is rather difficult to find specific information about this chemical, including its uses, safety concerns, and physical properties, suggesting that it might not be widely used or studied and also having a complex and unique structure, which makes it challenging for chemical synthesis.

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1010074-85-7 (3aR,4R,5R,6aS)-benzoic acid 4-[(1E)-3-hydroxy-oct-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 
• 39746-01-5 (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one 
• 40834-86-4 (3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester 

Downstream Products

• 60203-57-8 prostaglandin J₂ 
• 587869-87-2 (5Z)-7-{(1RS,2SR,5RS)-2-[(1E,3SR)-3-(tert-butyldimethylsilanyloxy)oct-1-enyl]-5-(2-nitrophenylselanyl)cyclopent-3-enyl}hept-5-enoic acid methyl ester 

Relevant articles and documents

First enantioselective total synthesis of (8S,12R,15S)-prostaglandin J2

Enantioselective synthesis of natural PGJ2 has been accomplished for the first time starting from the commercially available enantiopure aldehyde 7 in 10% overall yield. The key reaction was a novel prostaglandin class interconversion, i.e., an