588-68-1

Basic information

• Product Name: BENZALDEHYDE AZINE
• Synonyms: 1,4-Diphenyl-2,3-diaza-1,3-butadiene;2-(PhenylMethylene)hydrazone Benzaldehyde;NSC 3269;(1E,2E)-1,2-dibenzylidenehydrazine;benzoaldehyde azine;benzalazin;Benzaldazin;Benzaldazine
• CAS NO: 588-68-1
• Molecular Formula: C₁₄H₁₂N₂
• Molecular Weight: 208.26
• EINECS: 209-627-6
• Product Categories: Aromatics;Intermediates;Miscellaneous Reagents
• Mol File: 588-68-1.mol
• Article Data: 65

Chemical Properties

• Melting Point: 92-93 °C(lit.)
• Boiling Point: 318.3°Cat760mmHg
• Flash Point: 138.3°C
• Appearance: /
• Density: 0.98g/cm³
• Vapor Pressure: 0.000681mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: 0-10°C
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• PKA: 6.72±0.50(Predicted)
• BRN: 2208840
• CAS DataBase Reference: BENZALDEHYDE AZINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZALDEHYDE AZINE(588-68-1)
• EPA Substance Registry System: BENZALDEHYDE AZINE(588-68-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: CU7571500
• TSCA: Yes
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 588-68-1(Hazardous Substances Data)

Usage

Description

BENZALDEHYDE AZINE is a pale yellow solid that is utilized in the synthesis of various symmetric and asymmetric azines, which possess a range of antibacterial and antifungal properties.

Uses

Used in Pharmaceutical Industry:
BENZALDEHYDE AZINE is used as a key intermediate for the synthesis of azines with antibacterial and antifungal activities. These azines are essential in the development of new drugs to combat resistant bacterial and fungal strains, addressing the growing need for effective treatments in the medical field.
Used in Chemical Research:
BENZALDEHYDE AZINE serves as a valuable compound in chemical research, particularly in the study of azine chemistry and its potential applications. Its synthesis and properties are of interest to researchers looking to understand the behavior of azines and their derivatives, which could lead to the discovery of new compounds with beneficial properties.

InChI:InChI=1/C14H12N2/c1-3-7-13(8-4-1)11-15-16-12-14-9-5-2-6-10-14/h1-12H

Upstream product

• 5157-08-4 3-methyl-4,5-dihydro-6-oxopyridazine 
• 100-52-7 benzaldehyde 
• 908094-04-2 phenyldiazomethane 
• 114220-88-1 {Ta(O-2,6-C6H3-i-Pr2)3(THF)}2(μ-N2) 
• 114198-89-9 {Ta(S-2,4,6-C6H2-i-Pr3)3(THF)}2(μ-N2) 
• 916329-38-9 hydrogen azide 
• 56-23-5 tetrachloromethane 
• 5281-18-5 benzaldehyde, hydrazone 
• 729-44-2 1,2-bis[chloro(phenyl)methylidene]hydrazone 
• 1574-10-3 benzaldehyde semicarbazone 
• 65-85-0 benzoic acid 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 107-13-1 acrylonitrile 
• 126-98-7 methacrylonitrile 

Downstream Products

• 71284-90-7 N-[1-Phenyl-meth-(Z)-ylidene]-N'-[3,3,3-trifluoro-1-trifluoromethyl-prop-(E)-ylidene]-hydrazine 
• 154640-63-8 4,8-Diphenyl-octahydro-2,6-dithia-3b,7b-diaza-dicyclopenta[a,e]pentalene 2,2,6,6-tetraoxide 
• 93366-76-8 1,3,5-Triphenyl-4-benzylideneamino-1,2,4-Δ2-triazoline 
• 93366-77-9 1,5-Diphenyl-3-(4-nitrophenyl)-4-benzylideneamino-1,2,4-Δ2-triazoline 
• 100-52-7 benzaldehyde 
• 50398-52-2 2,6-diphenyl-1,3,5,7-tetraazabicyclo[3.3.0]octane-4,8-dione-3,7-disulfonyl chloride 
• 251451-24-8 trans-3,7-dihydro-2,6-diphenyl-1,3,5,7-tetraazabicyclo[3.3.0]octane-4,8-dione 
• 93-58-3 benzoic acid methyl ester 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 16128-38-4 tetrahydro-3,7-diphenyl-[1,2,4]triazolo[1,2-a][1,2,4]-triazole-1,5-dithione 
• 134898-18-3 benzaldehyde azine-3,3'-disulfonyl chloride 
• 120106-62-9 4,5-diphenyl-2H-1,2,3-triazole 

Relevant articles and documents

Unexpected reaction of dibenzyl disulfide with hydrazine

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N-Amino-1,8-Naphthalimide is a Regenerated Protecting Group for Selective Synthesis of Mono-N-Substituted Hydrazines and Hydrazides

A new route to synthesis of various mono-N-substituted hydrazines and hydrazides by involving in a new C?N bond formation by using N-amino-1,8-naphthalimide as a regenerated precursor was invented. Aniline and phenylhydrazines are reproduced upon reacting these individually with 1,8-naphthalic anhydride followed by hydrazinolysis. The practicality and simplicity of this C?N dihalo alkanes; developed a synthon for bond formation protocol was exemplified to various hydrazines and hydrazides. N-amino-1,8-naphthalimide is suitable synthon for transformation for selective formation of mono-substituted hydrazine and hydrazide derivatives. Those are selective mono-amidation of hydrazine with acid halides; mono-N-substituted hydrazones from aldehydes; synthesis of N-aminoazacycloalkanes from acetohydrazide scaffold and inserted to hydroxy derivatives; distinct synthesis of N,N-dibenzylhydrazines and N-benzylhydrazines from benzyl halides; synthesis of N-amino-amino acids from α-halo esters. Ecofriendly reagent N-amino-1,8-naphthalimide was regenerated with good yields by the hydrazinolysis in all procedures.

Conversion of Ammonia to Hydrazine Induced by High-Frequency Ultrasound

Hydrazine is a chemical of utmost importance in our society, either for organic synthesis or energy use. The direct conversion of NH3 to hydrazine is highly appealing, but it remains a very difficult task because the degradation of hydrazine is thermodynamically more feasible than the cleavage of the N?H bond of NH3. As a result, any catalyst capable of activating NH3 will thus unavoidably decompose N2H4. Here we show that cavitation bubbles, created by ultrasonic irradiation of aqueous NH3 at a high frequency, act as microreactors to activate and convert NH3 to NH species, without assistance of any catalyst, yielding hydrazine at the bubble–liquid interface. The compartmentation of in-situ-produced hydrazine in the bulk solution, which is maintained close to 30 °C, advantageously prevents its thermal degradation, a recurrent problem faced by previous technologies. This work also points towards a path to scavenge .OH radicals by adjusting the NH3 concentration.