588-88-5

Basic information

• Product Name: 4-Carbamyl-1-piperazinecarboxylic acid benzyl ester
• Synonyms: 4-Carbamyl-1-piperazinecarboxylic acid benzyl ester;Hibital
• CAS NO: 588-88-5
• Molecular Formula: C₁₃H₁₇N₃O₃
• Molecular Weight: 263.29
• Mol File: 588-88-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 470°C at 760 mmHg
• Flash Point: 238°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 5.28E-09mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 4-Carbamyl-1-piperazinecarboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Carbamyl-1-piperazinecarboxylic acid benzyl ester(588-88-5)
• EPA Substance Registry System: 4-Carbamyl-1-piperazinecarboxylic acid benzyl ester(588-88-5)

Safety Data

• Hazardous Substances Data: 588-88-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H17N3O3/c14-12(17)11-3-1-10(2-4-11)9-19-13(18)16-7-5-15-6-8-16/h1-4,15H,5-9H2,(H2,14,17)

Upstream product

• 556-89-8 nitrourea 
• 31166-44-6 phenylmethyl 1-piperazinecarboxylate 
• 68160-42-9 benzyl piperazine-1-carboxylate hydrochloride 
• 1118-02-1 trimethylsilyl isocyanate 
• 57-13-6 urea 

Downstream Products

• 5623-95-0 1-piperazine carboxamide 

Relevant articles and documents

Regioselective Formal [3+2] Cycloadditions of Urea Substrates with Activated and Unactivated Olefins for Intermolecular Olefin Aminooxygenation

A new class of intermolecular olefin aminooxygenation reaction is described. This reaction utilizes the classic halonium intermediate as a regio- and stereochemical template to accomplish the selective oxyamination of both activated and unactivated alkenes. Notably, urea chemical feedstock can be directly introduced as the N and O source and a simple iodide salt can be utilized as the catalyst. This formal [3+2] cycloaddition process provides a highly modular entry to a range of useful heterocyclic products with excellent selectivity and functional-group tolerance.