58808-68-7Relevant articles and documents
(: Z)-Selective anti-Markovnikov or Markovnikov thiol-yne-click reactions of an internal alkyne by amide hydrogen bond control
Pramanik, Milan,Choudhuri, Khokan,Chakraborty, Subhayan,Ghosh, Arindam,Mal, Prasenjit
supporting information, p. 2991 - 2994 (2020/03/19)
Herein, we show exclusive control of stereo and regioselective thiol-yne click (TYC) reactions of internal alkynes via amide hydrogen bond control. By exploiting appropriate hydrogen bonding interactions like N-H?S, N-H?N and C-H?O, either (Z)-selective anti-Markovnikov or Markovnikov products could be obtained for an internal alkyne, exclusively.