58810-67-6Relevant articles and documents
Chemoenzymatic preparation of enantiopure isomers of 4-aminochroman-3-ol and 1-amino-1,2,3,4-tetrahydronaphthalen-2-ol
Recuero, Veronica,De Gonzalo, Gonzalo,Brieva, Rosario,Gotor, Vicente
, p. 4224 - 4230 (2007/10/03)
Enantiomerically pure N-protected cis-4-aminochroman-3-ol (key precursor in the synthesis of novel HIV second-generation protease inhibitors), its trans isomer and both cis- and trans-1-amino-1,2,3,4-tetrahydronaphthalen-2-ol, useful chiral catalysts in o
Indinavir analogues with blocked metabolism sites as HIV protease inhibitors with improved pharmacological profiles and high potency against PI-resistant viral strains
Cheng, Yuan,Zhang, Fengqi,Rano, Thomas A,Lu, Zhijian,Schleif, William A,Gabryelski, Lori,Olsen, David B,Stahlhut, Mark,Rutkowski, Carrie A,Lin, Jiunn H,Jin, Lixia,Emini, Emilio A,Chapman, Kevin T,Tata, James R
, p. 2419 - 2422 (2007/10/03)
Indinavir analogues with blocked metabolism sites show highly improved pharmacokinetic profiles in animals. The cis-aminochromanol substituted analogues exhibited excellent potency against both the wild-type (NL4-3) virus and protease inhibitor-resistant HIV strains.
Synthesis of [1]benzopyrano[3,4 b][1,4]oxazines as potential antidepressants
Julian,Matusiak
, p. 1179 - 1182 (2007/10/07)
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