58822-47-2 Usage
Description
Secoxyloganin is a secoiridoid glycoside with diverse biological activities, found in L. japonica and Poraqueiba sericea stems. It exhibits antimicrobial properties against E. coli and S. aureus, as well as cytotoxic effects on human dermal fibroblasts. Additionally, secoxyloganin demonstrates anti-inflammatory capabilities in vivo.
Uses
Used in Pharmaceutical Applications:
Secoxyloganin is used as a cytotoxic agent for its potential in targeting cancer cells due to its cytotoxic activity against human dermal fibroblasts (IC50 = 78.1 μM).
Used in Antimicrobial Applications:
Secoxyloganin is used as an antimicrobial agent for its effectiveness against E. coli and S. aureus bacteria, particularly when used at a concentration of 2 mg/disc in a disc assay.
Used in Anti-inflammatory Applications:
Secoxyloganin is used as an anti-inflammatory agent for its ability to prevent hen egg white lysozyme-induced decreases in tail vein blood flow, a marker of allergic inflammation, in hen egg white lysozyme-sensitized mice.
Check Digit Verification of cas no
The CAS Registry Mumber 58822-47-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,8,2 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 58822-47:
(7*5)+(6*8)+(5*8)+(4*2)+(3*2)+(2*4)+(1*7)=152
152 % 10 = 2
So 58822-47-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H24O11/c1-3-7-8(4-11(19)20)9(15(24)25-2)6-26-16(7)28-17-14(23)13(22)12(21)10(5-18)27-17/h3,6-8,10,12-14,16-18,21-23H,1,4-5H2,2H3,(H,19,20)/t7-,8+,10-,12-,13+,14-,16+,17+/m1/s1
58822-47-2Relevant articles and documents
SECOIRIDOID, COUMARIN AND SECOIRIDOID-COUMARIN GLUCOSIDES FROM FRAXINUS CHINENSIS
Kuwajima, Hiroshi,Morita, Masami,Takaishi, Kiyokazu,Inoue, Kenichiro,Fujita, Tetsuro,et al.
, p. 1277 - 1280 (2007/10/02)
Besides the known glucosides, oleuropein, neooleuropein and cichoriin, a new secoiridoid glucoside, frachinoside, was isolated from leaves of Fraxinus chinensis and its structure elucidated. Key Word Index: Fraxinus chinensis; Oleaceae; secoiridoid glucoside; frachinoside.
