58848-63-8Relevant articles and documents
Capillary electrophoretic separation of enantiomers of amino acids and amino acid derivatives using crown ether and cyclodextrin
Salami,Jira,Otto, Hans-Hartwig
, p. 181 - 185 (2007/10/03)
The capillary zone electrophoresis using (+)-18-crown-6-tetracarbonic acid as a chiral selector was a suitable method for the enantiomeric separation of racemates of amino acids and of some amino acid derivatives (esters, dipeptides). The influence of the chemical structure of the compounds on the separation was investigated. After optimization of the separation conditions, baseline separations were obtained for most racemates. The addition of acetonitrile and TBAB yielded an improvement of the separation. Improved selectivity was further observed by the application of a cyclodextrin, HP-β-CD, in combination with the crown ether.
High Stereoselectivity in the Deacylation of p-Nitrophenyl N-Acylphenylalanates by Bilayer Vesicular Systems which include Dipeptide-type Nucleophiles
Ohkubo, Katsutoshi,Matsumoto, Noriko,Ohta, Hidefumi
, p. 738 - 740 (2007/10/02)
The deacylation of p-nitrophenyl N-acylphenylalanates with bilayer vesicular systems comprising dipeptide-type nucleophiles and a cationic double chain surfactant resulted in high stereoselectivity (kLcat/kDcat = 29.6 at 25 deg C and 83.6 at 10 deg C) for the deacylation of p-nitrophenyl N-dodecanoylphenylalanate by the catalytic system of N-(N-benzyloxycarbonyl-L-leucyl)-L-histidine and N,N-didodecyl-N,N-dimethylammonium bromide.