58856-93-2 Usage
Description
Zymosan A, derived from Saccharomyces cerevisiae, is a particulate yeast cell wall preparation known for its immunostimulatory properties. It is commonly utilized in various biological and medical research applications due to its ability to activate immune responses and trigger specific cellular reactions.
Uses
Used in Immunology Research:
Zymosan A is used as a positive control for the activation of the complement cascade, a series of protein interactions that play a crucial role in the immune system's defense against pathogens.
Used in Respiratory Burst Assay:
In the field of cellular immunology, Zymosan A serves as a stimulant in respiratory burst (RB) assays, which measure the production of reactive oxygen species by immune cells, particularly neutrophils and macrophages, upon activation.
Used in Dairy Cow Performance Studies:
Zymosan A is used as a stimulant to assess its effects on the performance, immunity, heat shock protein, and apoptosis-related gene expressions of dairy cows under heat stress conditions, aiming to improve their overall health and productivity.
Used in Pharmacological Research:
As a stimulating agent in Krebs-Ringer phosphate (KRP) medium, Zymosan A is employed to investigate its potential impact on various physiological processes and to study the underlying mechanisms of action.
Used in Pain Research:
In the field of neuroscience and pain management, Zymosan A is used to induce thermal hyperalgesia in mice, a condition characterized by an increased sensitivity to painful stimuli, which helps researchers understand the mechanisms of pain perception and develop potential therapeutic strategies.
Biochem/physiol Actions
Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes. It is used to induce experimental sterile inflammation. In macrophages, zymosan-induced responses include the induction of proinflammatory cytokines, arachidonate mobilization, protein phosphorylation, and inositol phosphate formation. Zymosan A also raises cyclin D2 levels suggesting a role for the latter in macrophage activation besides proliferation. It potentiates acute liver damage after galactosamine injection suggesting that certain types of nonparenchymal cells other than Kupffer cells are involved in zymosan action. Zymosan A, a 13 beta glucan contributes to the development of organic dust-induced respiratory disease.
Check Digit Verification of cas no
The CAS Registry Mumber 58856-93-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,8,5 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 58856-93:
(7*5)+(6*8)+(5*8)+(4*5)+(3*6)+(2*9)+(1*3)=182
182 % 10 = 2
So 58856-93-2 is a valid CAS Registry Number.
