58915-13-2

Basic information

• Product Name: 2-benzooxazol-2-ylsulfanyl-N-(2-hydrazinocarbonyl-phenyl)-acetamide
• CAS NO: 58915-13-2
• Molecular Weight: 342.378
• Mol File: 58915-13-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzooxazol-2-ylsulfanyl-N-(2-hydrazinocarbonyl-phenyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzooxazol-2-ylsulfanyl-N-(2-hydrazinocarbonyl-phenyl)-acetamide(58915-13-2)
• EPA Substance Registry System: 2-benzooxazol-2-ylsulfanyl-N-(2-hydrazinocarbonyl-phenyl)-acetamide(58915-13-2)

Safety Data

• Hazardous Substances Data: 58915-13-2(Hazardous Substances Data)

Upstream product

• 2382-96-9 2-sulfanyl-1,3-benzoxazole 
• 58915-07-4 2-(2-benzooxazol-2-ylsulfanyl-acetylamino)-benzoic acid methyl ester 
• 58915-18-7 methyl N-(chloroacetyl)anthranilate 

Relevant articles and documents

Synthesis of substituted thiobenzoxazoles/benzothiazoles: inhibition of cellular respiratory and monoamine oxidase activities and anticonvulsant property

Several 2 (substituted alkoxy/hydrazinocarbonyl acetanilidothio) benzoxazoles/benzothiazoles were synthesized and characterized by their sharp melting points, elemental analyses, and IR spectra. All thiobenzoxazoles/benzothiazoles possessed low anticonvulsant activity, which was reflected by the 10-40% protection afforded by these compounds against pentylenetetrazol induced convulsions. All thiobenzoxazoles/benzothiazoles inhibited selectively the nicotinamide adenine dinucleotide (NAD) dependent oxidation of pyruvate, DL isocitrate, and α ketoglutarate by rat brain homogenates. NAD independent oxidation of succinate remained unaltered. All 2 (substituted hydrazinocarbonyl acetanilidothio) benzoxazoles/benzothiazoles inhibited monoamine oxidase activity of rat brain homogenates. Greater monoamine oxidase inhibition was observed with thiobenzothiazoles than with the corresponding thiobenzoxazoles. The low anticonvulsant activity possessed by these thiobenzoxazoles/benzothiazoles was found to be unrelated with their ability to inhibit cellular respiratory and monoamine oxidase activities of rat brain homogenates.