58943-42-3

Basic information

• Product Name: 2-(1,3-benzothiazol-2-ylsulfanyl)-N-[2-(hydrazinylcarbonyl)phenyl]acetamide
• CAS NO: 58943-42-3
• Molecular Formula: C₁₆H₁₄N₄O₂S₂
• Molecular Weight: 358.438
• Mol File: 58943-42-3.mol
• Article Data: 1

Chemical Properties

• Density: 1.47g/cm³
• Refractive Index: 1.742
• CAS DataBase Reference: 2-(1,3-benzothiazol-2-ylsulfanyl)-N-[2-(hydrazinylcarbonyl)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1,3-benzothiazol-2-ylsulfanyl)-N-[2-(hydrazinylcarbonyl)phenyl]acetamide(58943-42-3)
• EPA Substance Registry System: 2-(1,3-benzothiazol-2-ylsulfanyl)-N-[2-(hydrazinylcarbonyl)phenyl]acetamide(58943-42-3)

Safety Data

• Hazardous Substances Data: 58943-42-3(Hazardous Substances Data)

Usage

Molecular structure

Contains a benzothiazole ring and a hydrazinecarbonyl group.

Chemical classification

Acetamide derivative.

Usage

Utilized in various research and industrial applications.

Antimicrobial properties

Benzothiazole ring contributes to its antimicrobial and antifungal properties.

Synthesis applications

Hydrazinecarbonyl group serves as a building block in the synthesis of pharmaceuticals and agrochemicals.

Potential applications

May have uses in medicine, agriculture, and material science.

Research necessity

Further research is required to fully understand its uses and properties.

Upstream product

• 58915-10-9 2-(2-benzothiazol-2-ylsulfanyl-acetylamino)-benzoic acid methyl ester 
• 58915-18-7 methyl N-(chloroacetyl)anthranilate 
• 149-30-4 2-Mercaptobenzothiazole 

Relevant articles and documents

Synthesis of substituted thiobenzoxazoles/benzothiazoles: inhibition of cellular respiratory and monoamine oxidase activities and anticonvulsant property

Several 2 (substituted alkoxy/hydrazinocarbonyl acetanilidothio) benzoxazoles/benzothiazoles were synthesized and characterized by their sharp melting points, elemental analyses, and IR spectra. All thiobenzoxazoles/benzothiazoles possessed low anticonvulsant activity, which was reflected by the 10-40% protection afforded by these compounds against pentylenetetrazol induced convulsions. All thiobenzoxazoles/benzothiazoles inhibited selectively the nicotinamide adenine dinucleotide (NAD) dependent oxidation of pyruvate, DL isocitrate, and α ketoglutarate by rat brain homogenates. NAD independent oxidation of succinate remained unaltered. All 2 (substituted hydrazinocarbonyl acetanilidothio) benzoxazoles/benzothiazoles inhibited monoamine oxidase activity of rat brain homogenates. Greater monoamine oxidase inhibition was observed with thiobenzothiazoles than with the corresponding thiobenzoxazoles. The low anticonvulsant activity possessed by these thiobenzoxazoles/benzothiazoles was found to be unrelated with their ability to inhibit cellular respiratory and monoamine oxidase activities of rat brain homogenates.