58975-55-6

Basic information

• Product Name: Benzoic acid, 2-[(benzoylamino)thioxomethyl]hydrazide
• CAS NO: 58975-55-6
• Molecular Formula: C15H13N3O2S
• Molecular Weight: 299.353
• Mol File: 58975-55-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[(benzoylamino)thioxomethyl]hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[(benzoylamino)thioxomethyl]hydrazide(58975-55-6)
• EPA Substance Registry System: Benzoic acid, 2-[(benzoylamino)thioxomethyl]hydrazide(58975-55-6)

Safety Data

• Hazardous Substances Data: 58975-55-6(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 5351-66-6 benzoyl thiosemicarbazide 
• 98-88-4 benzoyl chloride 
• 79-19-6 thiosemicarbazide 
• 613-94-5 benzoic acid hydrazide 
• 532-55-8 Benzoyl isothiocyanate 
• 64-17-5 ethanol 
• 93-89-0 benzoic acid ethyl ester 
• 65-85-0 benzoic acid 

Downstream Products

• 3414-94-6 5-phenyl-1,2-dihydro-1,2,4-triazole-3-thione 
• 19948-90-4 N-(5-phenyl-1,3,4-thiadiazol-2-yl)benzamide 
• 1612-76-6 2-amino-5-phenyl-1,3,4-oxadiazole 
• 5378-59-6 2-(N-benzoyl)-amino-5-phenyl-[1,3,4]oxadiazole 
• 3916-80-1 2-(acetylamino)-5-phenyl-1,3,4-oxadiazole 
• 1609076-20-1 (Z)-methyl 2-((E)-3-benzoyl-2-(2-benzoylhydrazono)-4-oxothiazolidin-5-ylidene)acetate 

Relevant articles and documents

Synthesis and antituberculosis activity of new acylthiosemicarbazides designed by structural modification

Acylthiosemicarbazides 8a–n were designed by structural modification of lead Compound 7. The syntheses of 8a–n involve a five-step procedure starting from carboxylic acids. Compounds 8a–n were tested against three Mycobacterium tuberculosis strains to measure their inhibitory antituberculosis activities. These activities could be explained according to the presence or absence of the chlorine substituent in the aromatic ring of the amide joined to the thiosemicarbazide core. Thiosemicarbazide derivative 8n is a candidate for the development of novel antitubercular agents. Ongoing studies are focused on exploring the mechanism by which these compounds inhibit M. tuberculosis cell growth.

A useful synthesis of 2-acylamino-1,3,4-oxadiazoles from acylthiosemicarbazides using potassium iodate and the discovery of new antibacterial compounds

A useful method for the synthesis of 2-acylamino-1,3,4-oxadiazoles was developed. By using potassium iodate as an oxidant in water at 60 ?C, a wide range of 2-acylamino-1,3,4-oxadiazoles were afforded in moderate to excellent yields within two

Intramolecular hydrogen bonding and anion binding of N-benzamido-N′- benzoylthioureas

(Chemical Equation Presented) N-(p-Dimethylamino)benzoyl-N′- phenylthiourea as an N-acylthiourea is known to be unable to bind anions due to a strong intramolecular hydrogen bond (IHB). We show here that by inserting an amido group in the N′-phenyl side the newly designed N-benzamido-N′- benzoylthioureas, despite this IHB too, bind strongly to anions with binding constants on the order of 106-107 mol-1 L. Results suggest that potential anion receptors or organocatalysts could be developed on the basis of this framework with a wide structural diversity.