59022-79-6

Basic information

• Product Name: 2-(2-Methyl-1H-iMidazol-5-yl)acetonitrile
• Synonyms: 2-(2-Methyl-1H-iMidazol-5-yl)acetonitrile
• CAS NO: 59022-79-6
• Molecular Formula: C6H7N3
• Molecular Weight: 121.13988
• Mol File: 59022-79-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(2-Methyl-1H-iMidazol-5-yl)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Methyl-1H-iMidazol-5-yl)acetonitrile(59022-79-6)
• EPA Substance Registry System: 2-(2-Methyl-1H-iMidazol-5-yl)acetonitrile(59022-79-6)

Safety Data

• Hazardous Substances Data: 59022-79-6(Hazardous Substances Data)

Usage

Physical appearance

White crystalline solid The compound forms a white, crystal-like structure in its solid state.

Synthesis use

Pharmaceutical and agrochemical production It is used as a key component in creating various medicines and chemicals used in agriculture.

Chemical group

Imidazole derivative It belongs to a group of compounds derived from the imidazole structure, which is a five-membered ring containing a nitrogen atom.

Potential properties

Antifungal and antibacterial It has been studied for its possible ability to fight against fungal and bacterial infections.

Intermediate application

Production of organic compounds The compound serves as an intermediate in the synthesis of other organic compounds.

Precaution

Irritation risk It may cause irritation to the eyes, skin, or respiratory system if not handled properly.

Upstream product

• 143-33-9 sodium cyanide 
• 408325-19-9 5-Chloromethyl-2-methyl-1H-imidazole 
• 45533-87-7 2-Methyl-5-hydroxymethyl-imidazol 
• 59022-78-5 4(5)-(chloromethyl)-2-methylimidazole hydrochloride 
• 45533-87-7 2-Methyl-4-hydroxymethyl-imidazol 
• 35034-22-1 2-methylimidazole-4⁽⁵⁾-carbaldehyde 

Relevant articles and documents

5-Substituted imidazole-4-acetic acid analogues: Synthesis, modeling, and pharmacological characterization of a series of novel γ-aminobutyric acidC receptor agonists

A series of ring-substituted analogues of imidazole-4-acetic acid (IAA, 4), a partial agonist at both GABAA and GABAC receptors (GABA = γ-aminobutyric acid), have been synthesized. The synthesized compounds 8a-1 have been evaluated a

Imidazole-containing inhibitors of farnesyl protein transferase

Inhibition of farnesyl transferase, which is an enzyme involved in ras oncogene expression, is effected by compounds of the formula their enantiomers, diastereomers, and pharmaceutically acceptable salts, prodrugs, and solvates, wherein:, G is G1 is G2 is or -NR10-CH(Q1)-;, J, K and L are each, independently, N, NR9, O, S or CR10 with the provisos that only one of the groups J, K and L can be O or S, and at least one of the groups J or L must be N, NR9, O or S to form a fused five-membered heteroring; the bond between J and K or K and L may also form one side of a phenyl ring fused to the fused five-membered heteroring;, Q is aryl;, Q1, A1 and A2 are each, independently, H, alkyl, substituted alkyl, phenyl or substituted phenyl;, G3 is R11, -C(O)OR11, -C(O)NR11R12, 5-tetrazolyl, -C(O)N(R13)OR11, -C(O)NHSO2R14 or -CH2OR11;, G4 is attached at the 1, 2, 4 or 5 position and optionally substituted, at any of the available position or positions on the ring, with halo, alkyl or substituted alkyl having 1 to 20 carbon atoms, alkoxy, aryl, aralkyl, hydroxy, alkanoyl, alkanoyloxy, amino, alkylamino, dialkylamino, alkanoylamino, thiol, alkylthio, alkylthiono, alkylsulfonyl, sulfonamido, nitro, cyano, carboxy, carbamyl, N-hydroxycarbamyl, N-alkylcarbamyl, N-dialkylcarbamyl, alkoxycarbonyl, phenyl, substituted phenyl, or a combinaton of these groups;, Y and Z are each, independently, -CH2- or -C(O)-;, R1 - R14 are each, independently, H or alkyl having 1 to 20 carbon atoms;, R7, R8 and R14 may also be aryl or aralkyl, and R3, R9, R11, R12 and R13 may also be aralkyl;, m, n and p are each, independently, 0 or an integer from 1 to 2;, q is 0 or an integer from 1 to 4; and, the dotted line represents an optional double bond.