590417-56-4 Usage
General Description
B-(1-methyl-1H-indol-4-yl)-Boronic acid is a chemical compound with the formula C10H12BNO2. It is a boronic acid derivative that contains a boron atom, along with a methyl group and an indol-4-yl group. B-(1-methyl-1H-indol-4-yl)-Boronic acid is commonly used in organic synthesis and pharmaceutical research, particularly in the development of new medications and bioactive molecules. Boronic acids are known for their ability to form reversible covalent bonds with certain functional groups, making them useful in medicinal chemistry for targeting specific biological receptors and enzymes. Additionally, B-(1-methyl-1H-indol-4-yl)-Boronic acid can be used as a reagent in various chemical reactions, such as Suzuki and Sonogashira coupling reactions, for the construction of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 590417-56-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,0,4,1 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 590417-56:
(8*5)+(7*9)+(6*0)+(5*4)+(4*1)+(3*7)+(2*5)+(1*6)=164
164 % 10 = 4
So 590417-56-4 is a valid CAS Registry Number.
590417-56-4Relevant articles and documents
Scope of the palladium-catalyzed aryl borylation utilizing bis-boronic acid
Molander, Gary A.,Trice, Sarah L. J.,Kennedy, Steven M.,Dreher, Spencer D.,Tudge, Matthew T.
supporting information; experimental part, p. 11667 - 11673 (2012/09/05)
The Suzuki-Miyaura reaction has become one of the more useful tools for synthetic organic chemists. Until recently, there did not exist a direct way to make the most important component in the coupling reaction, namely the boronic acid. Current methods to make boronic acids often employ harsh or wasteful reagents to prepare boronic acid derivatives and require additional steps to afford the desired boronic acid. The scope of the previously reported palladium-catalyzed, direct boronic acid synthesis is unveiled, which includes a wide array of synthetically useful aryl electrophiles. It makes use of the newly available second generation Buchwald XPhos preformed palladium catalyst and bis-boronic acid. For ease of isolation and to preserve the often sensitive C-B bond, all boronic acids were readily converted to their more stable trifluoroborate counterparts.
