5909-47-7

Basic information

• Product Name: (2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide
• Synonyms: (2E)-2-Cyano-3-[5-(2-methyl-4-nitrophenyl)-2-furyl]-N-(2-methylphenyl)acrylamide; 2-propenamide, 2-cyano-3-[5-(2-methyl-4-nitrophenyl)-2-furanyl]-N-(2-methylphenyl)-, (2E)-
• CAS NO: 5909-47-7
• Molecular Formula: C₁₂H₁₁N₃O₅
• Molecular Weight: 387.3881
• Mol File: 5909-47-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 621.2°C at 760 mmHg
• Flash Point: 329.5°C
• Density: 1.319g/cm³
• Vapor Pressure: 2.35E-15mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: (2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide(5909-47-7)
• EPA Substance Registry System: (2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide(5909-47-7)

Safety Data

• Hazardous Substances Data: 5909-47-7(Hazardous Substances Data)

Upstream product

• 5153-67-3 nitrostyrene 
• 67-52-7 BARBITURIC ACID 
• 877-24-7 potassium hydrogen phthalate 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 100-52-7 benzaldehyde 

Relevant articles and documents

A greener, efficient approach to michael addition of barbituric acid to nitroalkene in aqueous diethylamine medium

An efficient method for the synthesis of a variety of pyrimidine derivatives 3a-t by reaction of barbituric acids 1a,b as Michael donor with nitroalkenes 2a-k as Michael acceptor using an aqueous medium and diethylamine is described. This 1,4-Addition strategy offers several advantages, such as using an economic and environmentally benign reaction media, high yields, versatility, and shorter reaction times. The synthesized compounds were identified by 1H-NMR, 13C-NMR, CHN, IR, and MS. The structure of compound 3a was further confirmed by single crystal X-ray structure determination.