59101-27-8Relevant articles and documents
A simple technique to grow polymer brushes using in situ surface ligation of an organometallic initiator
Dronavajjala, Krishna D.,Rajagopalan, Ramakrishnan,Uppili, Sundararajan,Sen, Ayusman,Allara, David L.,Foley, Henry C.
, p. 13040 - 13041 (2006)
A simple approach is described here for the in-place synthesis of polymer brushes by surface-initiated polymerization. A cyano-terminated self-assembled monolayer on a gold surface was used to anchor a highly active cationic Pd organometallic initiator by ligand exchange. We grew ultrasmooth patterned poly(4-methoxystyrene) brushes with excellent thickness control at room temperature. Copyright
Synthesis of [3]rotaxanes that utilize the catalytic activity of a macrocyclic phenanthroline-Cu complex: Remarkable effect of the length of the axle precursor
Yamashita, Yoshiaki,Mutoh, Yuichiro,Yamasaki, Ryu,Kasama, Takeshi,Saito, Shinichi
, p. 2139 - 2145 (2015/02/19)
[3]Rotaxanes, which consist of one macrocyclic phenanthroline compound and two axle components, were prepared by the oxidative dimerization of an alkyne compound with bulky tris[4'-cyclohexyl-(1,1'-biphenyl)-4-yl]methyl blocking group. The catalytic activ
New fluorinated agonists for targeting the sphingosin-1-phosphate receptor 1 (S1P1)
Shaikh, Rizwan S.,Keul, Petra,Sch?fers, Michael,Levkau, Bodo,Haufe, Günter
, p. 5048 - 5051 (2015/11/09)
The sphingosine-1-phosphate receptor type 1 (S1P1) is involved in fundamental biological processes such as regulation of immune cell trafficking, vascular barrier function and angiogenesis. This Letter presents multistep syntheses of various fluorine substituted 12-aryl analogues of the drug fingolimod (FTY720) and a seven-steps route to 2-amino-17,17-difluoro-2-(hydroxymethyl)heptadecan-1-ol. In vitro and in vivo tests proved all these compounds as potent S1P1 receptor agonists.