5912-36-7 Usage
Description
1,7-Naphthyridin-6-amine(9CI) is a chemical compound with the molecular formula C9H7N3. It is a derivative of the heterocyclic compound naphthyridine, which consists of a seven-membered ring fused to a six-membered ring containing nitrogen atoms. 1,7-Naphthyridin-6-amine(9CI) has potential applications in medicinal chemistry and drug development due to its ability to interact with biological targets and potentially exhibit pharmacological properties. It is important to handle and use this chemical with caution, following proper safety protocols and guidelines to prevent potential harm to human health and the environment.
Uses
Used in Medicinal Chemistry:
1,7-Naphthyridin-6-amine(9CI) is used as a building block for the synthesis of various pharmaceutical compounds for [application reason]. Its unique structure allows it to form stable complexes with biological targets, making it a promising candidate for the development of new drugs.
Used in Drug Development:
1,7-Naphthyridin-6-amine(9CI) is used as a potential therapeutic agent for [application reason]. Its ability to interact with biological targets suggests that it may have pharmacological properties that can be harnessed for the treatment of various diseases and conditions.
Used in Chemical Research:
1,7-Naphthyridin-6-amine(9CI) is used as a research tool in the field of chemistry for [application reason]. Its unique structure and properties make it an interesting subject for studies aimed at understanding the behavior of heterocyclic compounds and their interactions with biological systems.
Note: The specific application reasons for medicinal chemistry, drug development, and chemical research are not provided in the materials. They should be filled in based on the actual applications and properties of 1,7-Naphthyridin-6-amine(9CI).
Check Digit Verification of cas no
The CAS Registry Mumber 5912-36-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,1 and 2 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5912-36:
(6*5)+(5*9)+(4*1)+(3*2)+(2*3)+(1*6)=97
97 % 10 = 7
So 5912-36-7 is a valid CAS Registry Number.
InChI:InChI=1/C26H34F3NO4S/c1-5-7-9-21(6-2)25(31)30(17-19(3)4)18-20-12-14-23(15-13-20)34-35(32,33)24-11-8-10-22(16-24)26(27,28)29/h8,10-16,19,21H,5-7,9,17-18H2,1-4H3
5912-36-7Relevant articles and documents
METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS
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, (2021/11/06)
The subject matter described herein is directed to ferroportin inhibitor compounds of Formula (I) and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis, and also kidney injuries.
Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: Discovery and structure-activity relationships of a series of quinoline and quinoxaline derivatives
Nishimura, Nobuko,Siegmund, Aaron,Liu, Longbin,Yang, Kevin,Bryan, Marian C.,Andrews, Kristin L.,Bo, Yunxin,Booker, Shon K.,Caenepeel, Sean,Freeman, Daniel,Liao, Hongyu,McCarter, John,Mullady, Erin L.,San Miguel, Tisha,Subramanian, Raju,Tamayo, Nuria,Wang, Ling,Whittington, Douglas A.,Zalameda, Leeanne,Zhang, Nancy,Hughes, Paul E.,Norman, Mark H.
, p. 4735 - 4751 (2011/09/20)
The phosphoinositide 3-kinase (PI3K) family catalyzes the ATP-dependent phosphorylation of the 3′-hydroxyl group of phosphatidylinositols and plays an important role in cell growth and survival. There is abundant evidence demonstrating that PI3K signaling is dysregulated in many human cancers, suggesting that therapeutics targeting the PI3K pathway may have utility for the treatment of cancer. Our efforts to identify potent, efficacious, and orally available PI3K/mammalian target of rapamycin (mTOR) dual inhibitors resulted in the discovery of a series of substituted quinolines and quinoxalines derivatives. In this report, we describe the structure-activity relationships, selectivity, and pharmacokinetic data of this series and illustrate the in vivo pharmacodynamic and efficacy data for a representative compound.
A new synthesis of 1,7-naphthyridine
Tan, Rosita,Taurins, Alfred
, p. 1233 - 1237 (2007/10/04)
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