59134-90-6

Basic information

• Product Name: N-(2-Bromo-thiazol-4-yl)-2,2,2-trifluoro-acetamide
• Synonyms: N-(2-Bromo-thiazol-4-yl)-2,2,2-trifluoro-acetamide;2-BroMo-4-trifluoroacetaMidothiazole;N-(2-Bromo-4-thiazolyl)-2,2,2-trifluoroacetamide
• CAS NO: 59134-90-6
• Molecular Formula: C₅H₂BrF₃N₂OS
• Molecular Weight: 275
• Mol File: 59134-90-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 323.6°C at 760 mmHg
• Flash Point: 149.5°C
• Appearance: /
• Density: 1.996g/cm³
• Vapor Pressure: 0.000259mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(2-Bromo-thiazol-4-yl)-2,2,2-trifluoro-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Bromo-thiazol-4-yl)-2,2,2-trifluoro-acetamide(59134-90-6)
• EPA Substance Registry System: N-(2-Bromo-thiazol-4-yl)-2,2,2-trifluoro-acetamide(59134-90-6)

Safety Data

• Hazardous Substances Data: 59134-90-6(Hazardous Substances Data)

Usage

General Description

N-(2-Bromo-thiazol-4-yl)-2,2,2-trifluoro-acetamide is a chemical compound that is a derivative of thiazole, a five-membered heterocyclic ring that contains sulfur and nitrogen atoms. It also contains a trifluoro-acetamide group, which is a functional group composed of a trifluoromethyl group attached to an amide. N-(2-Bromo-thiazol-4-yl)-2,2,2-trifluoro-acetamide is likely to be of interest for pharmaceutical or agricultural applications, as thiazole derivatives are known to have various biological activities, such as antimicrobial, antiviral, and antifungal properties. The presence of the trifluoro-acetamide group may also enhance the compound's bioavailability and pharmacokinetic properties. However, as with any chemical, thorough testing and evaluation of its safety and efficacy would be necessary before it could be used in practical applications.

InChI:InChI=1/C5H2BrF3N2OS/c6-4-11-2(1-13-4)10-3(12)5(7,8)9/h1H,(H,10,12)

Upstream product

• 41731-33-3 2-bromo-4-aminothiazole 
• 407-25-0 trifluoroacetic anhydride 
• 41731-35-5 2‐bromo‐1,3‐thiazol‐4‐amine hydrobromide 
• 127-09-3 sodium acetate 

Downstream Products

• 59134-92-8 4-trifluoroacetamidothiazole 

Relevant articles and documents

Self-assembly of bidentate ligands for combinatorial homogeneous catalysis: Methanol-stable platforms analogous to the adenine-thymine base pair

(Chemical Equation Presented) Complementary partners: A combinatorial library of self-assembled ligand systems has been designed by analogy to the A-T base pair. When these ligand systems are applied in the rhodium-catalyzed hydroformylation of 1-octene (

Anti-ulcer composition

The invention relates to pharmaceutical compositions for use in treating ulcers or hypersecretion in mammals comprising a compound of formula Ia STR1 WHERE Hal is a halogen atom, R1 is hydrogen or alkyl of 1-6 carbon atoms, R is hydrogen, alkyl of 1-5 carbon atoms (which may be substituted by two or more chlorine or bromine atoms), alkenyl of 2 to 5 carbon atoms, perfluoroalkyl of 1-5 carbon atoms, cycloalkyl of 3 to 5 carbon atoms, R3 is hydrogen, alkyl of 1-6 carbon atoms, or COR4 where R4 is as defined for R and R and R4 may be the same or different, and a pharmaceutically acceptable carrier. Methods of treatment of affected mammals and some novel compounds are also described.

4-Sulfanilamidothiazole

4-Sulfanilamidothiazole having antibacterial activity is prepared from the previously unknown 4-aminothiazole.