59142-47-1 Usage
Description
(2-BROMOPHENYL)(PHENYL)METHANOL, also known as 2-bromo-1-(phenylmethyl)benzene, is a chemical compound with the molecular formula C13H11BrO. It is a pale yellow to brown crystalline solid that is used as a building block in organic synthesis and pharmaceutical research. (2-BROMOPHENYL)(PHENYL)METHANOL contains both a bromine atom and a hydroxyl group attached to a benzene ring, making it a valuable intermediate in the production of various pharmaceuticals and agrochemicals. Its unique structure and reactivity make it an important compound for the creation of diverse chemical products and solutions.
Uses
Used in Pharmaceutical Industry:
(2-BROMOPHENYL)(PHENYL)METHANOL is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be easily modified and incorporated into complex molecular structures. Its presence in the molecular framework can contribute to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
(2-BROMOPHENYL)(PHENYL)METHANOL is used as a building block in the development of agrochemicals, such as pesticides and herbicides, due to its potential to enhance the effectiveness and selectivity of these compounds in agricultural applications.
Used in Organic Synthesis:
(2-BROMOPHENYL)(PHENYL)METHANOL is used as a versatile starting material in organic synthesis for the preparation of a wide range of chemical products. Its reactivity allows for various chemical reactions, leading to the formation of new compounds with different functional groups and properties.
Used in Research and Development:
(2-BROMOPHENYL)(PHENYL)METHANOL is used as a research compound to explore new chemical reactions and mechanisms, as well as to develop innovative methods for the synthesis of complex organic molecules. Its unique structure provides opportunities for scientists to study and understand the behavior of similar compounds in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 59142-47-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,1,4 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 59142-47:
(7*5)+(6*9)+(5*1)+(4*4)+(3*2)+(2*4)+(1*7)=131
131 % 10 = 1
So 59142-47-1 is a valid CAS Registry Number.
59142-47-1Relevant articles and documents
The intramolecular reaction of acetophenoneN-tosylhydrazone and vinyl: Br?nsted acid-promoted cationic cyclization toward polysubstituted indenes
Wang, Zhixin,Li, Yang,Chen, Fan,Qian, Peng-Cheng,Cheng, Jiang
, p. 1810 - 1813 (2021/02/27)
In the presence of TsNHNH2, a Br?nsted acid-promoted intramolecular cyclization ofo-(1-arylvinyl) acetophenone derivatives was developed, leading to polysubstituted indenes with complexity and diversity in moderate to excellent yields. In sharp contrast with either the radical or carbene involved cyclization of aldehydicN-tosylhydrazone with vinyl, a cationic cyclization pathway was involved, whereN-tosylhydrazone served as an electrophile and alkylation reagent during this transformation.
Highly Enantioselective Cobalt-Catalyzed Hydroboration of Diaryl Ketones
Liu, Wenbo,Guo, Jun,Xing, Shipei,Lu, Zhan
supporting information, p. 2532 - 2536 (2020/04/02)
A highly enantioselective cobalt-catalyzed hydroboration of diaryl ketones with pinacolborane was developed using chiral imidazole iminopyridine as a ligand to access chiral benzhydrols in good to excellent yields and ee. This protocol could be carried out in a gram scale under mild reaction conditions with good functional group tolerance. Chiral biologically active 3-substituted phthalide and (S)-neobenodine could be easily constructed through asymmetric hydroboration as a key step.
Asymmetric Synthesis of 1,2-Dihydronaphthalene-1-ols via Copper-Catalyzed Intramolecular Reductive Cyclization
Acharyya, Ranjan Kumar,Kim, Soyoung,Park, Yeji,Han, Jung Tae,Yun, Jaesook
supporting information, p. 7897 - 7902 (2020/11/02)
We describe a copper-catalyzed intramolecular reductive cyclization of easily accessible benz-tethered 1,3-dienes containing a ketone moiety. This process provided biologically active 1,2-dihydronaphthalene-1-ol derivatives in good yields with excellent enantio- and diastereoselectivity. Mechanistic investigations using density functional theory revealed that (Z)- and (E)-allylcopper intermediates formed in situ from the diene and copper catalyst undergo isomerization and selective intramolecular allylation of the (E)-allylcopper form of the major product through a six-membered boatlike transition state. The resulting products were further transformed to fully saturated naphthalene-1-ols by reactions of the olefin moiety.
