59181-30-5

Basic information

• Product Name: 2H-Indol-2-one, 1,3-dihydro-1-methyl-3-(phenylmethylene)-
• CAS NO: 59181-30-5
• Molecular Formula: C16H13NO
• Molecular Weight: 235.285
• Mol File: 59181-30-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 2H-Indol-2-one, 1,3-dihydro-1-methyl-3-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indol-2-one, 1,3-dihydro-1-methyl-3-(phenylmethylene)-(59181-30-5)
• EPA Substance Registry System: 2H-Indol-2-one, 1,3-dihydro-1-methyl-3-(phenylmethylene)-(59181-30-5)

Safety Data

• Hazardous Substances Data: 59181-30-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 61-70-1 N-methyl-2-indolinone 
• 201230-82-2 carbon monoxide 
• 27687-46-3 N-methyl-N-phenylcinnamamide 
• 100-42-5 styrene 
• 122100-99-6 3-phenyl-propynoic acid (2-iodo-phenyl)-methyl-amide 
• 208845-12-9 3-phenylpropynoic acid (2-iodo-phenyl)-amide 
• 637-44-5 phenylpropyolic acid 
• 615-43-0 2-iodophenylamine 
• 91-56-5 indole-2,3-dione 
• 2058-74-4 1-methyl-1H-indole-2,3-dione 
• 57056-93-6 N-methyl-2-iodoaniline 
• 94298-51-8 N-methyl-N,3-diphenylprop-2-ynamide 
• 1174751-04-2 diethyl (2-((2-bromophenyl)(methyl)amino)-2-oxoethyl)phosphonate 

Downstream Products

• 91208-61-6 dimethyl 2,3-diphenyloxirane-2,3-dicarboxylate 
• 107555-92-0 3-amino-1-methyl-4-phenylquinolin-2(1H)-one 
• 80356-42-9 4-Amino-1-methyl-3-phenyl-chinolin-2(1H)-on 

Relevant articles and documents

Oxidative electro-organic synthesis of dimeric hexahydropyrrolo-[2,3-: B] indole alkaloids involving PCET: Total synthesis of (±)-folicanthine

An efficient electrochemical oxidation strategy for the total synthesis of a dimeric hexahydropyrrolo[2,3-b]indole alkaloid, (±)-folicanthine (1b), has been envisioned. Control experiments suggest that a PCET pathway involving stepwise electron transfer f

Candida antarctica lipase-B-catalyzed kinetic resolution of 1,3-dialkyl-3-hydroxymethyl oxindoles

Candida antarctica (CAL-B) lipase-catalyzed resolution of 1,3-dialkyl-3-hydroxymethyl oxindoles has been performed to obtain (R)-1,3-dialkyl-3-acetoxymethyl oxindoles with up to 99% ee and (S)-1,3-dialkyl-3-hydroxymethyl oxindoles with up to 78% ee using vinyl acetate as acylating agent and acetonitrile as solvent transforming (S)-3-allyl-3-hydroxymethyl oxindole to (3S)-1′-benzyl-5-(iodomethyl)-4,5-dihydro-2H-spiro[furan-3,3′-indolin]-2′-one. The optically active 3-substituted-3-hydroxymethyl oxindoles and spiro-oxindoles are among the key synthons in the synthesis of potentially biologically active molecules.

Nucleophilic Ring Opening of Donor-Acceptor Cyclopropanes with the Cyanate Ion: Access to Spiro[pyrrolidone-3,3′-oxindoles]

The nucleophilic ring opening of donor-acceptor cyclopropanes with the cyanate ion is reported for the first time. Cyclopropanes, spiro-activated with oxindole fragments as acceptors, are shown to undergo transformations into biologically relevant spiro[pyrrolidone-3,3′-oxindoles] while being treated with potassium cyanate under microwave assistance.