59191-36-5

Basic information

• Product Name: dimethyl (((4-methylphenyl)sulfonamido)(phenyl)methyl)phosphonate
• Synonyms: dimethyl (((4-methylphenyl)sulfonamido)(phenyl)methyl)phosphonate
• CAS NO: 59191-36-5
• Molecular Weight: 369.378
• Mol File: 59191-36-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: dimethyl (((4-methylphenyl)sulfonamido)(phenyl)methyl)phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl (((4-methylphenyl)sulfonamido)(phenyl)methyl)phosphonate(59191-36-5)
• EPA Substance Registry System: dimethyl (((4-methylphenyl)sulfonamido)(phenyl)methyl)phosphonate(59191-36-5)

Safety Data

• Hazardous Substances Data: 59191-36-5(Hazardous Substances Data)

Upstream product

• 1416426-63-5 (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate 
• 100-52-7 benzaldehyde 
• 70-55-3 toluene-4-sulfonamide 
• 868-85-9 Dimethyl phosphite 
• 51608-60-7 phenyl N-tosyl imine 
• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 
• 36198-87-5 dimethyl trimethylsilyl phosphite 
• 186581-53-3 diazomethane 
• 59191-46-7 [Phenyl-(toluene-4-sulfonylamino)-methyl]-phosphonic acid 
• 96-36-6 methyl phosphite 

Downstream Products

• 1416426-63-5 (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate 
• 1416426-74-8 (S)-dimethyl (cyano(4-methylphenylsulfonamido)(phenyl)methyl)phosphonate 

Relevant articles and documents

Enantioselective Aza-Reformatsky Reaction with Ketimines

Here, an enantioselective aza-Reformatsky reaction using acyclic ketimine substrates is presented. Using α-phosphorated ketimines as electrophilic substrates and a simple BINOL-derived ligand, phosphorated analogues of aspartic acid holding chiral tetrasubstituted carbons are efficiently obtained with excellent enantioselectivity through an asymmetric organocatalytic Reformatsky-type reaction. The phosphorated analogues of aspartic acid have been used for the synthesis of phosphorus-containing enantiopure tetrasubstituted β-lactams.

Enantioselective Synthesis of α-Amino Phosphonates via Pd-Catalyzed Asymmetric Hydrogenation

A highly enantioselective palladium-catalyzed hydrogenation of a series of linear and cyclic α-iminophosphonates has been achieved, providing efficient access to optically active α-aminophosphonates with up to 99% ee. (Chemical Equation Presented).

Asymmetric cyanation of a-ketiminophosphonates catalyzed by cinchona alkaloids: Enantioselective synthesis of tetrasubstituted a-aminophosphonic acid derivatives from trisubstituted a-aminophosphonates

An enantioselective synthesis of tetrasubstituted a-phosphono-a-amino nitriles through asymmetric cyanation of a-ketiminophosphonates catalyzed by Cinchona alkaloids is reported. a-Ket- ACHTUNGTRENUNGiminophosphonates are generated, in a very efficient sy