592-51-8 Usage
Description
4-Pentenenitrile, also known as 4-PN, is a terminal alkene nitrile that exists as a colorless liquid. It is synthesized from 3-pentenenitrile through a cationic nickel hydride or cobalt catalyzed isomerization process. 4-Pentenenitrile is also capable of undergoing hydrocyanation in the presence of bidentate nickel complexes, which are used as catalysts, to produce 3-pentenenitrile. Additionally, 4-Pentenenitrile can participate in gas-phase reactions with OH radicals and Cl atoms when exposed to synthetic air and various reference compounds.
Uses
Used in Chemical Synthesis:
4-Pentenenitrile is used as a chemical intermediate for the synthesis of 4-pentenylamine, which is an important compound in the production of various chemicals and materials. The conversion of 4-PN to 4-pentenylamine is a crucial step in the manufacturing process of these products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Pentenenitrile may be utilized as a building block for the development of new drugs. Its unique chemical properties allow it to be a valuable component in the synthesis of various pharmaceutical compounds, potentially leading to the discovery of novel treatments and therapies.
Used in Material Science:
4-Pentenenitrile's ability to undergo gas-phase reactions with OH radicals and Cl atoms makes it a potential candidate for use in material science. It could be employed in the development of new materials with specific properties, such as improved resistance to degradation or enhanced reactivity in certain applications.
Used in Environmental Applications:
Due to its reactivity with OH radicals and Cl atoms, 4-Pentenenitrile may also find applications in environmental science. It could be used to study the behavior of pollutants in the atmosphere or to develop methods for the removal or neutralization of harmful substances.
Check Digit Verification of cas no
The CAS Registry Mumber 592-51-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,9 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 592-51:
(5*5)+(4*9)+(3*2)+(2*5)+(1*1)=78
78 % 10 = 8
So 592-51-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N/c1-2-3-4-5-6/h2H,1,3-4H2
592-51-8Relevant articles and documents
A convergent approach to indolines and indanes
Ly, Thi-My,Quiclet-Sire, Beatrice,Sortais, Benoit,Zard, Samir Z.
, p. 2533 - 2536 (1999)
Radical addition of a xanthate to an N-allylanilide or to a substituted 4-aryl-1-butene followed by cyclisation onto the aromatic ring provide the corresponding indoline or indane respectively.
Ni-Catalyzed hydrocyanation of alkenes with formamide as the cyano source
Shu, Xiao,Jiang, Yuan-Yuan,Kang, Lei,Yang, Luo
supporting information, p. 2734 - 2738 (2020/06/17)
CN generation from formamide dehydration! A novel Ni-catalyzed hydrocyanation of various alkenes to provide aliphatic nitriles is developed by generating hydrocyanic acid in situ from safe and readily available formamide. Excellent linear or branched regio-selectivity, wide substrate scope, cheap and stable nickel salt as a pre-catalyst, a safe cyano source, slow generation of CN to obviate catalyst deactivation and convenient experimental operation would render this hydrocyanation attactive for laboratory synthesis of aliphatic nitriles.
I2-Mediated oxidative bicyclization of 4-pentenamines to prolinol carbamates with CO2 incorporating oxyamination of the C=C bond
Wang, Sheng,Zhang, Xiaowei,Cao, Chengyao,Chen, Chao,Xi, Chanjuan
supporting information, p. 4515 - 4519 (2017/10/13)
A metal-free oxyamination reaction of alkenes with ambient CO2 is reported. In the presence of I2 and DBU, CO2 is applied in situ as a protecting group to regulate the nucleophilicity of the amino group and facilitate the bicyclization of 4-pentenamines with high chemoselectivity. Moreover, this reaction provided a feasible approach to prepare prolinol carbamates with good tolerance of functional groups and high efficiency under mild conditions.
