59227-74-6 Usage
General Description
1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-3-(tert-butylamino)propan-1-ol is a chemical compound with a complex structure. It contains a quinoline ring with two trifluoromethyl substituents at positions 2 and 8, as well as a tert-butylamino group attached to the third carbon of a propan-1-ol chain. 1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-3-(tert-butylamino)propan-1-ol may have potential applications in pharmaceuticals, as quinoline derivatives have been studied for their various biological activities, including antimalarial, antitumor, and antimicrobial properties. The presence of fluorine atoms in the molecule may also influence its chemical and physical properties, potentially making it useful in organic synthesis or materials science. Additionally, the tert-butylamino group could also impart specific characteristics to the compound, making it relevant in medicinal chemistry or as a building block in organic synthesis. Overall, the unique structure of 1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-3-(tert-butylamino)propan-1-ol suggests it could have diverse potential applications in various fields, particularly in the development of new pharmaceuticals or materials.
Check Digit Verification of cas no
The CAS Registry Mumber 59227-74-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,2,2 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 59227-74:
(7*5)+(6*9)+(5*2)+(4*2)+(3*7)+(2*7)+(1*4)=146
146 % 10 = 6
So 59227-74-6 is a valid CAS Registry Number.
59227-74-6Relevant articles and documents
Antimalarials. 7. 2,8 bis(trifluoromethyl) 4 quinolinemethanols
Blumbergs,Ao,LaMontagne,Markovac
, p. 1122 - 1126 (1975)
Based on the high antimalarial activity of α (2 piperidyl) 2,8 bis(trifluoromethyl) 4 quinolinemethanol, ten additional 2,8 bis(trifluoromethyl) 4 quinolinemethanols were prepared in which the amino alcohol side chain was structurally varied. Synthesis of the compounds is described and antimalarial activity data against Plasmodium berghei are presented and discussed in terms of the structure variations.
