59240-49-2

Basic information

• Product Name: 1-pentofuranosyl-5-(prop-2-en-1-yl)pyrimidine-2,4(1H,3H)-dione
• CAS NO: 59240-49-2
• Molecular Formula: C₁₂H₁₆N₂O₆
• Molecular Weight: 284.2652
• Mol File: 59240-49-2.mol
• Article Data: 2

Chemical Properties

• Density: 1.473g/cm³
• Refractive Index: 1.604
• CAS DataBase Reference: 1-pentofuranosyl-5-(prop-2-en-1-yl)pyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-pentofuranosyl-5-(prop-2-en-1-yl)pyrimidine-2,4(1H,3H)-dione(59240-49-2)
• EPA Substance Registry System: 1-pentofuranosyl-5-(prop-2-en-1-yl)pyrimidine-2,4(1H,3H)-dione(59240-49-2)

Safety Data

• Hazardous Substances Data: 59240-49-2(Hazardous Substances Data)

Usage

Type

Pyrimidine derivative
A compound derived from the pyrimidine core structure

Sugar moiety

Pentofuranosyl
A sugar group (pentose) attached to the pyrimidine core

Structure

Dihydropyrimidinone
A structure containing a pyrimidinone ring with two additional hydrogen atoms

Field of interest

Medicinal chemistry
The study of the compound's potential biological activities and pharmacological properties

Potential properties

Antiviral, antifungal, or antibacterial
The compound's structure suggests it may possess these properties

Potential application

Therapeutic agent for various diseases
The compound could be developed into a treatment for different diseases based on its properties

Further research

Necessary to understand properties and applications
More studies are needed to fully comprehend the compound's potential and possible uses

Upstream product

• 1024-99-3 5-iodouridine 
• 762-72-1 allyl-trimethyl-silane 

Relevant articles and documents

Photochemistry of 5- and 6-Iodouracils in the Presence of Allylsilanes and Alkenes. A Convenient Route to C5- and C6-Substituted Uracils

The photocoupling reaction of 5- and 6-iodouracil derivatives with allylsilanes and alkenes is presented.Irradiation of 5-iodouridine (5) and 5-iodo-2'-deoxyuridine (6) in the presence of allyltrimethylsilane in aqueous acetonitrile gave 5-allyluridine (7) and 5-allyl-2'-deoxyuridine, respectively.Irradiation of 6-iodo-1,3-dimethyluracil (11) in the presence of allylsilanes and alkyl-substituted olefins produced the corresponding C6-substituted uracil derivatives in good yields. 5-Fluoro-6-iodo-1,3-dimethyluracil (12) underwent a similar photocoupling reaction with allylsilanes and alkenes.The photocoupling reaction provides a convenient method for carbon-carbon bond formation at the C5 or C6 position of uracil derivatives.A radical addition mechanism has been proposed for this novel photocoupling reaction.