59247-63-1

Basic information

• Product Name: 1-amino-4-(methoxycarbonyl)pyridin-1-ium 2,4,6-trimethylbenzene-1-sulfonate
• Synonyms: 1-amino-4-(methoxycarbonyl)pyridin-1-ium 2,4,6-trimethylbenzene-1-sulfonate
• CAS NO: 59247-63-1
• Molecular Weight: 352.411
• Mol File: 59247-63-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-amino-4-(methoxycarbonyl)pyridin-1-ium 2,4,6-trimethylbenzene-1-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-amino-4-(methoxycarbonyl)pyridin-1-ium 2,4,6-trimethylbenzene-1-sulfonate(59247-63-1)
• EPA Substance Registry System: 1-amino-4-(methoxycarbonyl)pyridin-1-ium 2,4,6-trimethylbenzene-1-sulfonate(59247-63-1)

Safety Data

• Hazardous Substances Data: 59247-63-1(Hazardous Substances Data)

Upstream product

• 55-22-1 pyridine-4-carboxylic acid 
• 1239506-69-4 ethyl (1E)-N-(2,4,6-trimethylphenyl)sulfonyloxyethanimidate 
• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 
• 36016-40-7 mesitylenesulfonylhydroxylamine 

Downstream Products

• 99446-50-1 dimethyl pyrazolo[1,5-a]pyridine-3,5-dicarboxylate 
• 65966-19-0 2-phenyl-[1,2,4]triazolo[1,5-a]pyridine-7-carbaldehyde 

Relevant articles and documents

Synthesis and characterization of novel classes of PDE10A inhibitors - 1H-1,3-benzodiazoles and imidazo[1,2-a]pyrimidines

New compounds containing [1,2,4]triazolo [1,5-a]pyridine (I), pyrazolo [1,5-a]pyridine (II), 1H-1,3-benzodiazole (III) and imidazo [1,2-a]pyrimidine (IV) backbones were designed and synthesized for PDE10A interaction. Among these compounds, 1H-1,3-benzodiazoles and imidazo [1,2-a]pyrimidines showed the highest affinity for PDE10A enzyme as well as good metabolic stability. Both classes of compounds were identified as selective and potent PDE10A enzyme inhibitors.