592503-41-8

Basic information

• Product Name: Cyclopentanecarboxylic acid, 2-(acetylamino)-, ethyl ester, (1R,2S)- (9CI)
• Synonyms: Cyclopentanecarboxylic acid, 2-(acetylamino)-, ethyl ester, (1R,2S)- (9CI)
• CAS NO: 592503-41-8
• Molecular Formula: C10H17NO3
• Molecular Weight: 199.24688
• Product Categories: CYCLOPENTANE;AMINOACID
• Mol File: 592503-41-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopentanecarboxylic acid, 2-(acetylamino)-, ethyl ester, (1R,2S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 2-(acetylamino)-, ethyl ester, (1R,2S)- (9CI)(592503-41-8)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 2-(acetylamino)-, ethyl ester, (1R,2S)- (9CI)(592503-41-8)

Safety Data

• Hazardous Substances Data: 592503-41-8(Hazardous Substances Data)

Upstream product

• 29942-18-5 2-acetylaminocyclopent-1-enecarboxylic acid ethyl ester 
• 7149-18-0 ethyl 2-amino-1-cyclopentene-1-carboxylate 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 

Downstream Products

• 128052-92-6 (+)-(1S,2R)-2-aminocyclopentane-1-carboxylic acid hydrochloride 

Relevant articles and documents

Highly enantioselective asymmetric hydrogenation of β-acetamido dehydroamino acid derivatives using a three-hindered quadrant rhodium catalyst

(Chemical Equation Presented) A previously reported three-hindered quadrant chiral ligand and its corresponding rhodium complex provide high enantioselectivity for the asymmetric hydrogenation of β-acetamido dehydroamino acid substrates. Both (E)- and (Z)-substrates are hydrogenated with high enantioselectivity in all of the reported examples. Asymmetric hydrogenation of a cyclic β-acetamido dehydroamino acid substrate in 85% ee is also reported.

C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin

Materials and methods for preparing (S)-(+)-3-(aminomethyl)-5-methyl-hexanoic acid and structurally related compounds via enantioselective hydrogenation of prochiral olefins are disclosed. The methods employ novel chiral catalysts, which include C1-symmetric bisphosphine ligands bound to transition metals.

Enantioselective hydrogenation of tetrasubstituted olefins of cyclic β-(acylamino)acrylates

Hydrogenation of a series of cyclic β-(acylamino)acrylates with tetrasubstituted olefins has been accomplished successfully with the use of Ru catalysts with chiral biaryl ligands such as C3-TunaPhos, and up to over 99% ee's have been achieved. This methodology provides an efficient catalytic method for the synthesis of both cis and trans chiral cyclic β-amino acid derivatives. Copyright