59337-94-9

Basic information

• Product Name: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE)
• Synonyms: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE);1,1-diketothieno[2,3-d]isothiazol-3-one;1,1-dioxo-3-thieno[2,3-d]isothiazolone;1,1-dioxothieno[2,3-d][1,2]thiazol-3-one;1,1-dioxothieno[2,3-d]isothiazol-3-one;sodium thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide;1,1-dioxothieno[2,3-d][1,2]thiazol-3-olate
• CAS NO: 59337-94-9
• Molecular Formula: C5H3NO3S2
• Molecular Weight: 189.21222
• Mol File: 59337-94-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE)(59337-94-9)
• EPA Substance Registry System: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE)(59337-94-9)

Safety Data

• Hazardous Substances Data: 59337-94-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide (SALTDATA: FREE) is used as a reactant in the synthesis of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides, which are important intermediates for the development of new pharmaceutical compounds. These azol-1-yl derivatives exhibit potential biological activities, such as antifungal, antibacterial, and anti-inflammatory properties, making them valuable in the design of novel drugs for various medical applications.
Used in Chemical Synthesis:
In the field of organic chemistry, thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide (SALTDATA: FREE) serves as a key building block for the synthesis of a wide range of complex organic molecules. Its unique structure allows for various functional group transformations and reactions, enabling the creation of diverse chemical entities with potential applications in materials science, agrochemicals, and other specialty chemicals.
Used in Research and Development:
Thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide (SALTDATA: FREE) is also utilized in research and development laboratories for the exploration of new synthetic routes, reaction mechanisms, and the study of structure-activity relationships. Its unique chemical properties make it an interesting candidate for understanding the reactivity and selectivity of various synthetic transformations, contributing to the advancement of chemical knowledge and the development of new synthetic methodologies.

Upstream product

• 59337-93-8 Methyl 3-sulfamoylthiophene-2-carboxylate 
• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 
• 59337-92-7 2-(carbomethoxy)thiophene-3-sulfonyl chloride 
• 59337-78-9 4-(aminosulfonyl)-3-thiophenecarboxylic acid methyl ester 
• 59337-98-3 3-(N-tert-butylsulfamoyl)-thiophene-2-carboxylic acid 
• 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid 

Downstream Products

• 113387-66-9 3-Pyrazol-1-yl-thieno[2,3-d]isothiazole 1,1-dioxide 
• 113387-68-1 3-(3,5-Dimethyl-pyrazol-1-yl)-thieno[2,3-d]isothiazole 1,1-dioxide 
• 113387-67-0 3-(4-Chloro-pyrazol-1-yl)-thieno[2,3-d]isothiazole 1,1-dioxide 
• 113387-69-2 3-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-thieno[2,3-d]isothiazole 1,1-dioxide 
• 113387-70-5 1-(1,1-Dioxo-1H-1λ⁶-thieno[2,3-d]isothiazol-3-yl)-1H-indazole 
• 119120-83-1 1-(1,1-Dioxo-1H-1λ⁶-thieno[2,3-d]isothiazol-3-yl)-1H-benzotriazole 
• 94040-09-2 2,3-Dihydro-2-methyl-3-oxo-thieno<2,3-d>isothiazol-1,1-dioxid 
• 98827-44-2 methyl 4-hydroxy-2H-thieno<2,3-e>-1,2-thiazine-3-carboxylate 1,1-dioxide 
• 59804-25-0 4-hydroxy-3-methoxycarbonyl-2-methyl-2H-thieno[2,3-e]-1,2-thiazine,1,1-dioxide 

Relevant articles and documents

AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thieno isothiazole-1,1-dioxides

Three series of new 3-(azol-1-yl)thieno isothiazole-1,1-dioxides were synthesized and tested for anti-inflammatory and related pharmacological activities as well as for acute toxicity.Acetylsalicylic acid was used as the reference standard.Keywords - 3-(a