59338-87-3

Basic information

• Product Name: Alizapride hydrochloride
• Synonyms: 6-methoxy-n-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2h-benzotriazole-5-carboxamide hydrochloride;alizapride hydrochloride;Alizapride HCl;6-Methoxy-N-{[(2S)-1-(prop-2-en-1-yl)pyrrolidin-2-yl]Methyl}-2H-1,2,3-benzotriazole-5-carboxaMide;N-((1-Allylpyrrolidin-2-yl)methyl)-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide hydrochlori;N-((1-Allylpyrrolidin-2-yl)Methyl)-6-Methoxy-1H-benzo[d][1,2,3]triazole-5-carboxaMide hydrochloride;1H-Benzotriazole-5-carboxamide,6-methoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]-, hydrochloride (1:1);-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide hydrochloride
• CAS NO: 59338-87-3
• Molecular Formula: C16H22ClN5O2
• Molecular Weight: 351.83118
• EINECS: 261-710-6
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Inhibitors
• Mol File: 59338-87-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 206-208°
• Boiling Point: 580.3 °C at 760 mmHg
• Flash Point: 304.8 °C
• Appearance: COA
• Density: 1.224 g/cm³
• Vapor Pressure: 1.47E-14mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: Alizapride hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Alizapride hydrochloride(59338-87-3)
• EPA Substance Registry System: Alizapride hydrochloride(59338-87-3)

Safety Data

• Hazardous Substances Data: 59338-87-3(Hazardous Substances Data)

Usage

Description

Alizapride hydrochloride is a dopamine antagonist characterized by its prokinetic and antiemetic effects. It is a white to off-white solid and is known for its ability to block dopamine receptors, which contributes to its therapeutic applications.

Uses

Used in Pharmaceutical Industry:
Alizapride hydrochloride is used as an antiemetic agent for the treatment of post-operative nausea and vomiting. Its dopamine antagonist properties help in reducing the feelings of nausea and the occurrence of vomiting after surgery, providing relief and comfort to patients.
Additionally, due to its prokinetic effects, Alizapride hydrochloride may also be utilized in the treatment of other gastrointestinal disorders where increased gut motility is desired. However, this application is not explicitly mentioned in the provided materials and would require further research and validation.

InChI:InChI=1/C16H21N5O2.ClH/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2;/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20);1H