59360-03-1

Basic information

• Product Name: N-phosphono-L-glutamic acid
• Synonyms: L-glutamic acid, N-phosphono-
• CAS NO: 59360-03-1
• Molecular Formula: C₅H₁₀NO₇P
• Molecular Weight: 227.1092
• Mol File: 59360-03-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 562.9°C at 760 mmHg
• Flash Point: 294.3°C
• Density: 1.765g/cm³
• Vapor Pressure: 3.79E-14mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: N-phosphono-L-glutamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-phosphono-L-glutamic acid(59360-03-1)
• EPA Substance Registry System: N-phosphono-L-glutamic acid(59360-03-1)

Safety Data

• Hazardous Substances Data: 59360-03-1(Hazardous Substances Data)

Upstream product

• 56-86-0 L-glutamic acid 
• 560063-85-6 O,O-bis(2-cyanoethyl) methyl (S)-1-carbomethoxybutanoate phosphoroamidate 
• 6525-53-7 L-glutamic acid dimethyl ester 
• 23150-65-4 L-glutamic dimethyl ester hydrochloride 

Relevant articles and documents

Synthesis of N-phosphoryl amino acids using bis(9-fluorenylmethyl)phosphite

Bis(9-fluorenylmethyl)phosphite (BFMP) was found to be an effective reagent for the N-phosphorylation of various amino acid methyl esters. BFMP was prepared from N,N-diisopropyl phosphoramidous dichloride in a one-pot two-step reaction and was obtained as a crystalline solid. N-Phosphorylation of the methyl esters of seven representative amino acids with BFMP was high-yielding and generally resulted in crystalline products. Complete deprotection of both the 9-fluorenylmethylphosphosphate esters and the amino acid methyl esters was accomplished concomitantly with LiOH to give N-phosphoryl amino acids.