59389-72-9Relevant articles and documents
Improved Chemical Syntheses of 1- and 5-Deazariboflavin
Carlson, Erin E.,Kiessling, Laura L.
, p. 2614 - 2617 (2004)
The cofactor flavin adenine dinucleotide (FAD) is required for the catalytic activity of a large class of enzymes known as flavoenzymes. Because flavin cofactors participate in catalysis via a number of different mechanisms, isoalloxazine analogues are valuable for mechanistic studies. We report improved chemical syntheses for the preparation of the two key analogues, 5-deazariboflavin and 1-deazariboflavin.