594823-69-5

Basic information

• Product Name: 5-NAPHTHALEN-1-YL-BENZO[1,3]DIOXOLE
• Synonyms: 5-NAPHTHALEN-1-YL-BENZO[1,3]DIOXOLE;5-(1-naphthalenyl)-1,3-Benzodioxole
• CAS NO: 594823-69-5
• Molecular Formula: C17H12O2
• Molecular Weight: 248.28
• Mol File: 594823-69-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 396.2±42.0 °C(Predicted)
• Appearance: /
• Density: 1.241±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-NAPHTHALEN-1-YL-BENZO[1,3]DIOXOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-NAPHTHALEN-1-YL-BENZO[1,3]DIOXOLE(594823-69-5)
• EPA Substance Registry System: 5-NAPHTHALEN-1-YL-BENZO[1,3]DIOXOLE(594823-69-5)

Safety Data

• Hazardous Substances Data: 594823-69-5(Hazardous Substances Data)

Usage

General Description

5-NAPHTHALEN-1-YL-BENZO[1,3]DIOXOLE is a chemical compound with a naphthalene ring and a benzo[1,3]dioxole ring. It is commonly used in the synthesis of organic compounds and as a building block for pharmaceuticals. This chemical is known for its potential as a mutagenic agent and for its carcinogenic properties. It is important to handle 5-NAPHTHALEN-1-YL-BENZO[1,3]DIOXOLE with caution and adhere to proper safety protocols when working with this compound to avoid potential health risks.

Upstream product

• 90-11-9 1-Bromonaphthalene 
• 109586-40-5 1,3-dihydroisobenzofuran-5-yl trifluoromethanesulfonate 
• 703-55-9 1-naphthylmagnesiumbromide 
• 7228-38-8 5-chloro-1,3-benzodioxole 
• 1351445-39-0 N,N,N-trimethyl-1-naphthalenaminium trifluoromethanesulfonate 
• 94839-07-3 3,4-(methylenedioxy)-benzeneboronic acid 
• 86-56-6 N,N-dimethyl-1-naphthalenamine 

Relevant articles and documents

C(sp2)-C(sp2) Suzuki cross-coupling of arylammonium salts catalyzed by a stable Pd–NHC complex

We have developed the Suzuki-Miyaura cross-coupling of aryl ammonium salts via C–N bond activation catalyzed by an easily prepared and bench-stable palladium-N-heterocyclic carbene complex. The reaction proceeded well under mild conditions with phenylboronic acid, pinacol ester or anhydride and provided yields of products up to 97% with good functional group compatibility. The direct arylation of arylamine can be performed by a two-step one-pot process and the protocol can be performed on the gram scale.

Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines

Organozinc compounds of the type R1—Ar1—ZnY (1) can be reacted with different functionalized aryl halides R2—Ar2—X (2) in the presence of catalytic amounts of Ni or Fe in a polar solvent or solvent mixture to form polyfunctional biaryles of the type R1—Ar1—Ar2—R2 (3). Organozinc compounds of the type (1) can be represented by the transmetallation reaction of functionalized aryl magnesium halides or lithium aryl compounds with e.g. ZnBr2.

5,6,7,12-Tetrahydrodibenz[c,f][1,5]azabismocines: Highly reactive and recoverable organo-bismuth reagents for cross-coupling reactions with Aryl Bromides

Hypervalent organobismuth compounds efficiently couple with aryl bromides in the presence of [Pd(PPh3)4] catalyst. Application of this protocol to a one-pot multi-coupling reaction with bromophenylboronic esters leads to the formation of up to nine bonds in good yields (see scheme).