594836-76-7Relevant articles and documents
One-pot sequential asymmetric hydrogenation of β-aryl-β-aryloxy acroleins
Liu, Yufeng,Chen, Jianzhong,Zhang, Zhenfeng,Qin, Jian,Zhao, Min,Zhang, Wanbin
, p. 7099 - 7102 (2016/07/30)
A one-pot sequential asymmetric hydrogenation of β-aryl-β-aryloxy acroleins has been realized for the preparation of chiral 3-aryl-3-aryloxy alcohols with excellent yields and good enantioselectivities. This methodology can be employed in new synthetic routes for the synthesis of fluoxetine, atomoxetine, and related analogues.
Asymmetric synthesis of 2-substituted chroman-4-ones using lipase-catalyzed kinetic resolutions
Kawasaki, Masashi,Kakuda, Hiroko,Goto, Michimasa,Kawabata, Shigeki,Kometani, Tadashi
, p. 1529 - 1534 (2007/10/03)
2-Methylchroman-4-one and 2-phenylchroman-4-one were synthesized in optically active form. Their chiral intermediates were obtained via lipase-catalyzed enantioselective reactions.