59524-88-8

Basic information

• Product Name: 2-AMINO-4-HYDROXY-6-IODOPYRIMIDINE
• Synonyms: 2-AMINO-4-HYDROXY-6-IODOPYRIMIDINE;2-amino-6-iodo-3H-pyrimidin-4-one;2-Amino-6-iodopyrimidin-4-ol
• CAS NO: 59524-88-8
• Molecular Formula: C₄H₄IN₃O
• Molecular Weight: 237
• Mol File: 59524-88-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 477.754°C at 760 mmHg
• Flash Point: 242.737°C
• Appearance: /
• Density: 2.402g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.782
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-AMINO-4-HYDROXY-6-IODOPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-HYDROXY-6-IODOPYRIMIDINE(59524-88-8)
• EPA Substance Registry System: 2-AMINO-4-HYDROXY-6-IODOPYRIMIDINE(59524-88-8)

Safety Data

• Hazardous Substances Data: 59524-88-8(Hazardous Substances Data)

Usage

General Description

2-Amino-4-hydroxy-6-iodopyrimidine is a chemical compound with the molecular formula C4H4IN3O. It is a pyrimidine derivative with an amino group at position 2, a hydroxy group at position 4, and an iodine atom at position 6. 2-AMINO-4-HYDROXY-6-IODOPYRIMIDINE is used in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential use as an antiviral and anticancer agent. 2-Amino-4-hydroxy-6-iodopyrimidine has demonstrated potential biological activity, making it of interest for further research and development in the pharmaceutical industry.

InChI:InChI=1/C4H4IN3O/c5-2-1-3(9)8-4(6)7-2/h1H,(H3,6,7,8,9)

Upstream product

• 56-05-3 2-Amino-4,6-dichloropyrimidine 
• 861031-48-3 4,6-diiodopyrimidin-2-ylamine 

Downstream Products

• 1000385-95-4 2-amino-6-iodopyrimidin-4-yl 4-methylbenzenesulfonate 
• 688782-34-5 3-(2-amino-6-oxo-1,6-dihydropyrimidin-4-yl)benzonitrile 
• 98305-67-0 2-Amino-6-(3-trifluoromethyl-phenyl)-3H-pyrimidin-4-one 
• 1393883-15-2 C₁₁H₁₁N₃O 
• 1574394-55-0 C₁₂H₁₀N₄O 
• 1574394-56-1 C₁₂H₇F₃N₄O 
• 1574394-54-9 C₁₁H₈F₃N₃O₂ 
• 1415309-89-5 5-(2-amino-6-oxo-1,6-dihydropyrimidin-4-yl)-2-isobutoxybenzonitrile 

Relevant articles and documents

Sonogashira cross-coupling in the synthesis of acyclic nucleoside phosphonates: Preparation of 6-[(phosphonomethoxy)alkynyl]- and 6-[(phosphonomethoxy)alkyl]pyrimidines

Several 6-[(phosphonomethoxy)alkyl]pyrimidines and 6-[(phosphonomethoxy) alkynyl]-pyrimidines were prepared as saturated and unsaturated carba-analogues of antivirally active 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidine. As the key step of their s

2-Amino-6-iodo-4-tosyloxypyrimidine: a versatile key intermediate for regioselective functionalization of 2-aminopyrimidines in 4- and 6-positions

2-Amino-6-iodo-4-tosyloxypyrimidine, easily prepared from commercially available material, is a key intermediate for the preparation of differentially substituted 2-aminopyrimidines by means of sequenced Suzuki and/or Sonogashira reactions.