595607-51-5Relevant articles and documents
A potent and highly selective inhibitor of human α-1,3-fucosyltransferase via click chemistry
Lee, Lac V.,Mitchell, Michael L.,Huang, Shih-Jung,Fokin, Valery V.,Sharpless, K. Barry,Wong, Chi-Huey
, p. 9588 - 9589 (2007/10/03)
Potent inhibitors of fucosyltransferases, and glycosyltransferases in general, have been elusive due to the inherent barriers surrounding the family of glycosyltransfer reactions. The problems of weak substrate affinity and low catalytic proficiency of fu