59563-95-0

Basic information

• Product Name: (1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-p-tolyl-methanone
• Synonyms: (1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-p-tolyl-methanone
• CAS NO: 59563-95-0
• Molecular Weight: 314.346
• Mol File: 59563-95-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-p-tolyl-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-p-tolyl-methanone(59563-95-0)
• EPA Substance Registry System: (1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-p-tolyl-methanone(59563-95-0)

Safety Data

• Hazardous Substances Data: 59563-95-0(Hazardous Substances Data)

Upstream product

• 5334-48-5 4-chloro-1-(phenyl)-1H-pyrazolo[3,4-d]pyrimidine 
• 104-87-0 4-methyl-benzaldehyde 
• 187875-68-9 1-methyl-2-(α-hydroxy-4-methylbenzyl)imidazole 
• 187875-25-8 1-methyl-2-(α-hydroxy-4-methylbenzyl)benzimidazole 

Relevant articles and documents

Synthesis and reactivities of 1,3-dimethyl-2-(α-hydroxy-benzyl)imidazolium and 1,3-dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodides

1,3-Dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodide (3a) was synthesized from 1-methylbenzimidazole (10) through two steps involving lithiation and quaternization. Treatment of 3a with 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (6) afforded 4-benzoyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (15a). 4-Benzoylquinazoline (14a) and 7-benzoyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (16a) were given by reaction of 3a with 4-chloroquinazoline (5) and 7-chloro-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (7). Treatment of 3a with benzaldehyde (9a) gave benzoin (8a). Similar results were obtained in the reactions of 1,3-dimethyl-2-(α-hydroxybenzyl)imidazolium iodide (4a).

Catalytic action of azolium salts. I. Aroylation of 4-chloro-1H-pyrazolo[3,4-d]pyrimidines with aromatic aldehydes catalyzed by 1,3-dimethylbenzimidazolium iodide

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