59576-25-9

Basic information

• Product Name: Methanone, (2-methyl-4-pyridinyl)phenyl-
• CAS NO: 59576-25-9
• Molecular Formula: C13H11NO
• Molecular Weight: 197.236
• Mol File: 59576-25-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Methanone, (2-methyl-4-pyridinyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-methyl-4-pyridinyl)phenyl-(59576-25-9)
• EPA Substance Registry System: Methanone, (2-methyl-4-pyridinyl)phenyl-(59576-25-9)

Safety Data

• Hazardous Substances Data: 59576-25-9(Hazardous Substances Data)

Upstream product

• 22282-99-1 4-bromo-2-methylpyridine 
• 611-73-4 Benzoylformic acid 
• 1115492-92-6 2-methyl-4-pyridylzinc bromide 
• 98-88-4 benzoyl chloride 
• 79534-90-0 2-methyl-4-(trimethylstannyl)pyridine 

Relevant articles and documents

DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF

Methods described herein enable the production of numerous molecular species through decarboxylative cross-coupling via use of photoredox and transition metal catalysts. For example, methods described herein enable the production of numerous molecular species through decarboxylative cross-coupling via use of photoredox and transition metal catalysts. A method described herein, in some embodiments, comprises providing a reaction mixture including a photoredox catalyst, a transition metal catalyst, a coupling partner and a substrate having a carboxyl group. The reaction mixture is irradiated with a radiation source resulting in cross-coupling of the substrate and coupling partner via a mechanism including decarboxylation, wherein the coupling partner is selected from the group consisting of a substituted aromatic compound and a substituted aliphatic compound.

Preparation 2-substituted-4-pyridylzinc bromides via direct insertion of active zinc and their coupling reactions

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Studies on Organometallic Compounds. III. Reaction of Trimethylstannylazines with Acyl Chlorides. A Novel C-C Bond Formation of Pyridine Nuclei

Introduction of an acyl group at the α-, β-, and γ-positions of pyridine nuclei was accomplished. 2-Trimethylstannyl-pyridine and -quinoline and 1-trimethylstannylisoquinoline directly reacted with various acyl chlorides to give the corresponding 2-pyridyl, 2-quinolyl, and 1-isoquinolyl ketones, respectively.Reaction of 3-trimethylstannylpyridine, -quinoline, and -isoquinoline with acyl chlorides proceeded smoothly under catalysis by PdCl2 or PdCl2(PPh3)2 to afford the corresponding ketones in good yields.Similary, 4-pyridyl, -quinolyl, and -isoquinolyl ketones were prepared from corresponding 4-trimethylstannyl derivatives and acyl chlorides.Keywords--trimethylstannylazine; palladium-catalyzed reaction; acylation; palladium dichloride; dichlorobis(triphenylphosphine)palladium(II)