59576-98-6Relevant articles and documents
METHODS OF REDUCING VIRULENCE IN BACTERIA
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Page/Page column 76; 88, (2011/09/19)
A method of reducing virulence in a bacterium comprising at least one of a GacS/GacA-type system, a HrpX/HrpY-type system, a T3SS-type system, and a Rsm-type system, the method comprising contacting the bacterium with an effective amount of a compound described herein.
Isolation and Activity of N-p-Coumaroyltyramine, an α-Glucosidase Inhibitor in Welsh Onion (Allium fistulosum)
Nishioka, Tetsuo,Watanabe, Jun,Kawabata, Jun,Niki, Ryoya
, p. 1138 - 1141 (2007/10/03)
A phenolic amide, N-p-coumaroyltyramine (1), was isolated as an α-glucosidase inhibitor from methanol extracts of Welsh onion (Allium fistulosum). The inhibitory activity of 1 against a yeast enzyme was as high as Ki 8.4 × 10-7 M. From a structure-activity relationship study of 1 and its related compounds, the occurrence of α-glucosidase inhibitory activity required a p-coumaramide structure, with an amide hydrogen and alkyl or aralkyl substituent on the amide part.
COMPARATIVE REACTIVITY OF NITRILES OF PARA-SUBSTITUTED CINNAMIC ACIDS IN THE ALKYLATION OF BENZENE IN THE PRESENCE OF ALUMINUM CHLORIDE
Grebenyuk, A. D.,Grinshpun, V. D.,L'vov, V. M.
, p. 732 - 736 (2007/10/02)
The relative rate constants for the reactions of the nitriles of p-methoxy, p-methyl, and p-chlorocinnamic acids with benzene in the presence of aluminum chloride were determined by the method of competing reactions in relation to cinnamonitrile.The negative sign of ρ indicates that the electrophilic stage of complex formation between the unsaturated nitrile and aluminum chloride has a deciding role in the alkylation process.
