59607-99-7

Basic information

• Product Name: ETHYL 3-(3-PYRIDYL)ACRYLATE
• Synonyms: 3-Pyridin-3-ylacrylicacidethylester;Ethyl (E)-3-(3-pyridinyl)-2-propenoate
• CAS NO: 59607-99-7
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.19984
• Product Categories: Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides
• Mol File: 59607-99-7.mol
• Article Data: 43

Chemical Properties

• Boiling Point: 90-92°C/1 mm
• Flash Point: 126.3°C
• Appearance: /
• Density: 1.106g/cm³
• Vapor Pressure: 0.00284mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: Refrigerator
• CAS DataBase Reference: ETHYL 3-(3-PYRIDYL)ACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-(3-PYRIDYL)ACRYLATE(59607-99-7)
• EPA Substance Registry System: ETHYL 3-(3-PYRIDYL)ACRYLATE(59607-99-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 59607-99-7(Hazardous Substances Data)

Usage

Description

ETHYL 3-(3-PYRIDYL)ACRYLATE, with the CAS number 59607-99-7, is a colorless oil compound that is widely utilized in the field of organic synthesis. Its unique chemical structure and properties make it a valuable component in the creation of various complex organic molecules.

Uses

Used in Organic Synthesis:
ETHYL 3-(3-PYRIDYL)ACRYLATE is used as a key intermediate for the synthesis of a variety of organic compounds. Its application in this field is due to its ability to participate in various chemical reactions, such as polymerization and cross-linking, which are essential for the development of new materials and pharmaceuticals.
Used in Pharmaceutical Industry:
ETHYL 3-(3-PYRIDYL)ACRYLATE is used as a building block for the development of novel pharmaceutical compounds. Its application in this industry is attributed to its potential role in the synthesis of new drugs with improved therapeutic properties and reduced side effects.
Used in Polymer Industry:
ETHYL 3-(3-PYRIDYL)ACRYLATE is used as a monomer in the production of specialty polymers. Its application in this industry is due to its ability to form copolymers with other monomers, resulting in materials with enhanced properties, such as improved mechanical strength, thermal stability, and chemical resistance.
Used in Chemical Research:
ETHYL 3-(3-PYRIDYL)ACRYLATE is used as a research tool for studying various chemical reactions and mechanisms. Its application in this field is because of its unique reactivity and the opportunity it provides for understanding the behavior of similar compounds in different reaction conditions.

InChI:InChI=1/C10H11NO2/c1-2-13-10(12)6-5-9-4-3-7-11-8-9/h3-8H,2H2,1H3/b6-5+

Upstream product

• 54495-51-1 (E)-3-(2-pyridyl)acrylic acid 
• 500-22-1 3-pyridinecarboxaldehyde 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 141-78-6 ethyl acetate 
• 105-36-2 ethyl bromoacetate 
• 462-08-8 pyridin-3-ylamine 
• 140-88-5 ethyl acrylate 
• 1126-74-5 3-(pyridin-3-yl)acrylic acid 
• 64-17-5 ethanol 
• 19337-97-4 trans-3-(3-pyridyl)acrylic acid 
• 75-03-6 ethyl iodide 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 845457-63-8 3-(4-trimethylsilanylpyridin-3-yl)-acrylic acid ethyl ester 
• 626-55-1 3-Bromopyridine 

Downstream Products

• 69963-46-8 3-(pyridin-3-yl)prop-2-en-1-ol 
• 19337-97-4 trans-3-(3-pyridyl)acrylic acid 
• 120277-39-6 trans-3-(pyridin-3-yl)-allyl alcohol 
• 28447-15-6 trans-3-(3-pyridyl)acrolein 
• 210565-12-1 (R,S)-1-{3(R)-[N-(tert-butyloxycarbonyl)-3-piperidinyl]propyl}-2-[(4-chlorophenoxy)methyl]-4-({3(S)-[N-(tert-butyloxycarbonyl)-3-piperidinyl]propyl}oxy)benzimidazole 
• 193627-94-0 (R,R)-1-{3(R)-[N-(tert-butyloxycarbonyl)-3-piperidinyl]propyl}-2-[(4-chlorophenoxy)methyl]-4-({3(R)-[N-(tert-butyloxycarbonyl)-3-piperidinyl]propyl}oxy)benzimidazole 
• 193627-96-2 (S,S)-1-{3(S)-[N-(tert-butyloxycarbonyl)-3-piperidinyl]propyl}-2-[(4-chlorophenoxy)methyl]-4-({3(S)-[N-(tert-butyloxycarbonyl)-3-piperidinyl]propyl}oxy)benzimidazole 
• 210565-05-2 (S,R)-1-{3(S)-[N-(tert-butyloxycarbonyl)-3-piperidinyl]propyl}-2-[(4-chlorophenoxy)methyl]-4-({3(R)-[N-(tert-butyloxycarbonyl)-3-piperidinyl]propyl}oxy)benzimidazole 
• 210223-01-1 tert-butyl (3R)-3-(3-ethoxy-3-oxopropyl)piperidine-1-carboxylate 
• 210564-95-7 (R)-3-{3-[2-(4-Chloro-phenoxymethyl)-4-hydroxy-benzoimidazol-1-yl]-propyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 210564-92-4 (S)-3-{3-[2-(4-Chloro-phenoxymethyl)-4-hydroxy-benzoimidazol-1-yl]-propyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 193628-06-7 (R)-3-{3-[4-Benzyloxy-2-(4-chloro-phenoxymethyl)-benzoimidazol-1-yl]-propyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 193628-07-8 (S)-3-{3-[4-Benzyloxy-2-(4-chloro-phenoxymethyl)-benzoimidazol-1-yl]-propyl}-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Photoinduced Regioselective Olefination of Arenes at Proximal and Distal Sites

The Fujiwara-Moritani reaction has had a profound contribution in the emergence of contemporary C-H activation protocols. Despite the applicability of the traditional approach in different fields, the associated reactivity and regioselectivity issues had

Copper-catalyzed Mizoroki-Heck coupling reaction using an efficient and magnetically reusable Fe3O4@SiO2@PrNCu catalyst

This study intends to design and prepare a new magnetic copper catalyst and its activity was assessed by carbon-carbon coupling reactions. For this purpose, 1-[3-(trimethoxysilyl) propyl] urea (TMSPU), hydrazine and CuI were used sequentially to modify Fe3O4@SiO2 core-shell magnetic nanoparticles to obtain an efficient magnetic transition metal catalyst. Various analytical techniques were used to characterize the catalyst to show that the achieved structure and its properties are well-suited for coupling reactions. Finally, Mizoroki-Heck and Ullmann coupling reactions were performed using Fe3O4@SiO2@PrNCu catalyst. The new catalyst offer simple synthetic procedure, convenient use for routine casework and low price. The Fe3O4@SiO2@PrNCu catalyst was easily separated by means of a permanent and ordinary magnet and the recovered catalyst was reused in six cycles without any significant loss of activity.

Bioactivity and structure–activity relationship of cinnamic acid derivatives and its heteroaromatic ring analogues as potential high-efficient acaricides against Psoroptes cuniculi

A series of cinnamic acid derivatives and its heteroaromatic ring analogues were synthesized and evaluated for acaricidal activity in vitro against Psoroptes cuniculi, a mange mite. Among them, eight compounds showed the higher activity with median lethal concentrations (LC50) of 0.36–1.07 mM (60.4–192.1 μg/mL) and great potential for the development of novel acaricidal agent. Compound 40 showed both the lowest LC50 value of 0.36 mM (60.4 μg/mL) and the smallest median lethal time (LT50) of 2.6 h at 4.5 mM, comparable with ivermectin [LC50 = 0.28 mM (247.4 μg/mL), LT50 = 8.9 h], an acaricidal drug standard. SAR analysis showed that the carbonyl group is crucial for the activity. The type and chain length of the alkoxy in the ester moiety and the steric hindrance near the ester group significantly influence the activity. The esters were more active than the corresponding thiol esters, amides, ketones or acids. Replacement of the phenyl group of cinnamic esters with α-pyridyl or α-furanyl significantly increase the activity. Thus, a series of cinnamic esters and its heteroaromatic ring analogues with excellent acaricidal activity emerged.