596093-58-2

Basic information

• Product Name: Isoquinoline, 1,2-dihydro-2-(phenylmethyl)-1-(tribromomethyl)-
• CAS NO: 596093-58-2
• Molecular Formula: C17H14Br3N
• Molecular Weight: 472.017
• Mol File: 596093-58-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Isoquinoline, 1,2-dihydro-2-(phenylmethyl)-1-(tribromomethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoquinoline, 1,2-dihydro-2-(phenylmethyl)-1-(tribromomethyl)-(596093-58-2)
• EPA Substance Registry System: Isoquinoline, 1,2-dihydro-2-(phenylmethyl)-1-(tribromomethyl)-(596093-58-2)

Safety Data

• Hazardous Substances Data: 596093-58-2(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 119-65-3 isoquinoline 
• 75-25-2 Bromoform 
• 23277-04-5 2-benzylisoquinolin-2-ium bromide 

Relevant articles and documents

Silver nitrate-promoted ring enlargement of 1-tribromomethyl-1,2-dihydro- and 1-tribromomethyl-1,2,3,4-tetrahydro-isoquinoline derivatives: Application to the synthesis of the anti-anginal zatebradine

The one step AgNO3-mediated ring enlargement of 1-tribromomethyl-1,2-dihydro- and 1-tribromomethyl-1,2,3,4-tetrahydro-isoquinoline derivatives into 1,2-dihydro- and 1,2,3,4-tetrahydro-benzo[d]azepin-2-ones, respectively, is reported. This reaction offers a convenient entry to potentially active substances such as the anti-anginal zatebradine.