596115-20-7Relevant articles and documents
Effects of various bases on acid-catalyzed amination of 2-chloro-5-ethylpyrimidine: Synthesis of PPARpan agonist GW693085
Glover, Bobby N.,Jones, Lynda A.,Johnson, Byron S.,Millar, Alan,Osterhout, Martin H.,Xie, Shiping
supporting information; experimental part, p. 3904 - 3907 (2010/07/05)
Figure presented A unique buffering effect of various bases, i-Pr 2NEt and CaCO3 in particular, was observed for the acid-catalyzed chloro displacement of 2-chloro-5-ethylpyrimidine with a 2-methyl-2-phenylpropanamine. The use of the