59653-40-6 Usage
Description
1-Azabicyclo[2.2.2]octan-3-ol, acetate (ester), (R)is a chiral bicyclic organic compound commonly known as (R)-3-Hydroxy-1-azabicyclo[2.2.2]octane acetate. It is an ester of (R)-3-Hydroxy-1-azabicyclo[2.2.2]octane, which features a unique ring structure. 1-Azabicyclo[2.2.2]octan-3-ol, acetate (ester), (R)is widely recognized for its applications in the pharmaceutical and chemical industries, particularly as a chiral building block in the synthesis of various drugs and pharmaceuticals. Its potential extends to medicinal chemistry, where it plays a role in the development of new drugs for neurological and psychiatric disorders. Furthermore, it has been investigated for its use as a chiral resolving agent in chromatography and as a ligand in asymmetric catalysis.
Uses
Used in Pharmaceutical Industry:
1-Azabicyclo[2.2.2]octan-3-ol, acetate (ester), (R)is used as a chiral building block for the synthesis of various drugs and pharmaceuticals. Its unique structure allows for the creation of enantiomerically pure compounds, which is crucial in ensuring the desired therapeutic effects and minimizing potential side effects.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Azabicyclo[2.2.2]octan-3-ol, acetate (ester), (R)is utilized in the development of new drugs for neurological and psychiatric disorders. Its chiral properties enable the design of more effective and targeted treatments, addressing the specific needs of these complex conditions.
Used in Chromatography:
1-Azabicyclo[2.2.2]octan-3-ol, acetate (ester), (R)is employed as a chiral resolving agent in chromatography. This application leverages its ability to selectively interact with enantiomers, facilitating the separation and analysis of chiral compounds, which is essential in various chemical and pharmaceutical processes.
Used in Asymmetric Catalysis:
As a ligand in asymmetric catalysis, 1-Azabicyclo[2.2.2]octan-3-ol, acetate (ester), (R)plays a significant role in enhancing the selectivity and efficiency of catalytic reactions. This contributes to the production of enantiomerically pure products, which is particularly important in the synthesis of pharmaceuticals and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 59653-40-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,6,5 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 59653-40:
(7*5)+(6*9)+(5*6)+(4*5)+(3*3)+(2*4)+(1*0)=156
156 % 10 = 6
So 59653-40-6 is a valid CAS Registry Number.
59653-40-6Relevant articles and documents
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Shaw
, p. 3264,3267 (1965)
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PHARMACEUTICAL COMPOSITION FOR USE IN MEDICAL AND VETERINARY OPHTHALMOLOGY
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, (2012/05/04)
The invention relates to pharmaceutics, medicine, in particular to manufacturing and use of pharmaceutical compositions of medicines (ophthalmic preparations) comprising mitochondria-addressed antioxidant and a set of auxiliary substances providing effective treatment for ophtalmological diseases in humans and animals.
Synthesis of the optical isomers of a new anticholinergic drug, penehyclidine hydrochloride (8018)
Han, Xiang-Yu,Liu, He,Liu, Chun-He,Wu, Bo,Chen, Lan-Fu,Zhong, Bo-Hua,Liu, Ke-Liang
, p. 1979 - 1982 (2007/10/03)
A practical diastereoselective synthetic method for 8018 enantiopure isomers is described. The intramolecular asymmetric epoxidation of mono-sulfonate 4 was applied for the execution of the synthesis of the key chiral building block for the first time. The isomers were obtained with 70-76% yields in 99-100% ee.
