59681-09-3

Basic information

• Product Name: 2-Methyl-2-(benzylthio)propylaMine
• Synonyms: 2-Methyl-2-(benzylthio)propylaMine;2-benzylsulfanyl-2-methylpropan-1-amine
• CAS NO: 59681-09-3
• Molecular Formula: C₁₁H₁₇NS
• Molecular Weight: 195.32438
• Product Categories: Amines, Sulfur & Selenium Compounds
• Mol File: 59681-09-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Solubility: Chloroform, Methanol
• CAS DataBase Reference: 2-Methyl-2-(benzylthio)propylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-2-(benzylthio)propylaMine(59681-09-3)
• EPA Substance Registry System: 2-Methyl-2-(benzylthio)propylaMine(59681-09-3)

Safety Data

• Hazardous Substances Data: 59681-09-3(Hazardous Substances Data)

Usage

Description

2-Methyl-2-(benzylthio)propylamine is a chemical compound that serves as a benzyl-protected derivative of 2-Methyl-2-thiopropylamine Hydrochloride (M326920). It is characterized by its unique structure, which includes a methyl group, a benzylthio group, and an amine functional group. 2-Methyl-2-(benzylthio)propylaMine is primarily utilized in the synthesis of biologically oriented organic sulfur compounds, which have potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
2-Methyl-2-(benzylthio)propylamine is used as an intermediate in the synthesis of biologically oriented organic sulfur compounds for the pharmaceutical industry. These compounds can be further developed into potential therapeutic agents, targeting various diseases and conditions.
Used in Chemical Research:
In the field of chemical research, 2-Methyl-2-(benzylthio)propylamine is used as a starting material or building block for the development of novel sulfur-containing molecules. These molecules can be explored for their potential applications in various areas, such as materials science, catalysis, and environmental chemistry.
Used in Synthesis of Sulfur-Containing Compounds:
2-Methyl-2-(benzylthio)propylamine is used as a key component in the synthesis of sulfur-containing compounds, which are essential in various chemical and pharmaceutical applications. These compounds can exhibit a range of properties, such as antioxidant, anti-inflammatory, and antimicrobial activities, making them valuable for the development of new drugs and materials.

Upstream product

• 75-52-5 nitromethane 
• 100-53-8 phenylmethanethiol 
• 67-64-1 acetone 
• 105780-12-9 benzyl(2-methyl-1-nitropropan-2-yl)sulfane 
• 304-59-6 Rochelle's salt 

Downstream Products

• 256505-80-3 N,N'-bis-(2-benzylthio-2-methylpropyl)-2-(benzylthiomethyl)-2-methylmalonyl diamide 
• 366490-40-6 N,N'-bis-(2-benzylthio-2-methylpropyl)-2-(benzylthioethyl)-2-methylmalonyl diamide 
• 133762-47-7 N-(2-dimethylphosphinothioylethyl)-2-benzylthio-2-methylpropylamine 
• 1313762-27-4 N-(2-(2-methyl-2-(benzylthio)propylcarbamoyl)propan-2-yl)-3-methyl-3-(benzylthio)butanamide 

Relevant articles and documents

Synthesis, silver (I) extraction and silver (I) binding studies of novel N 1,N 3-bis(2-(benzylthio)ethyl)propanediamide derivatives

Abstract: Solvent or liquid–liquid extraction represents a highly valuable technique for the selective recovery of metals from the aqueous phase due to the ease of operation and short turnaround times. Ligands bearing soft donor atoms including nitrogen and sulfur are ideal candidates for selective silver recovery due to their preference for silver binding. Herein, novel N1,N3-bis(2-(benzylthio)ethyl)propanediamide derivatives bearing sulfur and nitrogen donor atoms were prepared in low to high yields and tested for Ag+ extraction from ternary aqueous solutions also containing Cu2+ and Pb2+ following a well-established solvent extraction protocol. It was observed that electronics effects at the 4-aryl position in the propanediamide (or malondiamide) derivatives had a significant effect on the selectivity, but little effect on the efficiency of Ag+ extraction with the 4-methoxy analogue proving the most selective. Steric hindrance provided by dimethyl substitutions at the α-positions to the sulfur atoms had negative effects on Ag+ extraction efficiency and selectivity, while diethyl steric hindrance at the methylene center lowered selectivity but increased extraction efficiency for Ag+. Detailed binding studies reveal that one of the malondiamide derivatives which lacked the electronic and steric hindrance groups studied coordinated Ag+ in a 1:1 fashion suggesting a tetrahedral complex geometry. Overall, the results show that simple modification of the electronics and sterics of the N1,N3-bis(2-(benzylthio)ethyl)propanediamides, can improve their selectivity for Ag+ recovery from the aqueous phase. Graphic abstract: [Figure not available: see fulltext.].

Cationic complexes of technetium-99M

Tridentate mono-anionic ligands have the structure where each of X and Y is independently P, As or N, Z is phenol, thiophenol or thiol, and A and Q are hydrocarbon linking groups. The ligands from cationic complexes with Technetium-99m, e.g. [TcIII K2 ]+ where K is the ligand, having useful imaging properties.