59699-82-0Relevant articles and documents
Stereocontrolled synthesis of 13-substituted retinoic acids by palladium-catalyzed coupling reaction of alkenyl stannane with vinyl triflate
Wada,Fukunaga,Ito
, p. 800 - 802 (2007/10/03)
A novel method for the stereoselective synthesis of all-E-, 13Z- and 9Z- retionic acid esters was developed by palladium-catalyzed cross coupling reactions of tetraenyl stannanes with E- or Z-vinyl triflates in good yields. Applying this methodology, 13-substituted all-E- and 9Z- retinoic acids were prepared in satisfactory yields.
Synthesis of New Aromatic Retinoid Analogues by Low-Valent Titanium Induced Reductive Elimination
Solladie, Guy,Girardin, Andre,Lang, Gerard
, p. 2620 - 2628 (2007/10/02)
The low-valent titanium reductive elimination reaction, already applied to the stereospecific synthesis of vitamin A and 13-cis-retinol, was used to prepare several retinoic acid analogues in the all-trans configuration or in the 13-cis configuration.This highly stereospecific trans-diene formation allowed an improved synthesis of the title compounds without any purification of the intermediates before the final stage.
7-cis,9-cis,11-cis-retinal, all-cis-vitamin A, and 7-cis,9-cis,11-cis-12-fluororetinal. New geometric isomers of vitamin A and carotenoids. 12
Asato,Kini,Denny,Liu
, p. 2923 - 2924 (2007/10/02)
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