59700-86-6Relevant articles and documents
General Synthesis of α-Alkyl Ynones from Morpholine Amides and 1-Copper(I) Alkynes Promoted by Triflic Anhydride
Weng, Yunxiang,Min, Lin,Zeng, Xiaobao,Shan, Lidong,Wang, Xinyan,Hu, Yuefei
, p. 8296 - 8301 (2020)
The first general method for the synthesis of α-alkyl ynones was developed based on the strategy of electrophilic activation of amides. Its distinctive advantages are attributed to the use of air-stable "bare"1-copper(I) alkyne as a mild nucleophile witho