59703-84-3 Usage
Description
Piperacillin sodium salt, also known as Piperacillin sodium, is a semi-synthetic antibiotic derived from the penicillin group. It is a broad-spectrum antibiotic that is effective against a wide range of both gram-positive and gram-negative bacteria. Piperacillin sodium salt is a white to off-white crystalline powder and is commonly known by the brand name Pipracil, specifically manufactured by Wyeth.
Uses
Used in Pharmaceutical Industry:
Piperacillin sodium salt is used as a broad-spectrum antibiotic for treating various bacterial infections. It targets a wide range of susceptible gram-positive and gram-negative bacteria, making it a versatile choice in the treatment of different types of infections.
Used in Antimicrobial Therapy Optimization:
In the field of pharmacokinetic studies, Piperacillin sodium salt is utilized to optimize antimicrobial therapy. This involves studying the drug's absorption, distribution, metabolism, and excretion to ensure the most effective dosage and treatment regimen for patients.
Used in Hypersensitivity Reactions:
Piperacillin sodium salt is also used in the management of hypersensitivity reactions, which are adverse immune responses to certain medications, including antibiotics. It helps in diagnosing and treating these reactions to ensure patient safety during antibiotic treatment.
Used in Study of Multidrug-Resistant Organisms:
The antibiotic is involved in the study of multidrug-resistant organisms, which are bacteria that have developed resistance to multiple antibiotics. Research on Piperacillin sodium salt contributes to the development of new strategies and treatments to combat these resistant bacteria and improve overall public health.
Check Digit Verification of cas no
The CAS Registry Mumber 59703-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,7,0 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 59703-84:
(7*5)+(6*9)+(5*7)+(4*0)+(3*3)+(2*8)+(1*4)=153
153 % 10 = 3
So 59703-84-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1
59703-84-3Relevant articles and documents
Piperacillin sodium compound containing half water
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Paragraph 0029; 0032-0035; 0037; 0040-0043; 0045-0048, (2019/01/23)
The invention discloses a piperacillin sodium compound containing half water and a preparation method thereof. Each mole of piperacillin sodium contains a half mole of water. First, ampicillin trihydrate is reacted with 4-ethyl-2,3-dioxypiperazine formyl chloride to form piperacillin acid, then piperacillin acid is reacted with sodium acetate in a mixed solution of acetone and water, isopropanol is added dropwise, and crystallization, filtration and drying are conducted to obtain the piperacillin sodium compound containing half water. The piperacillin sodium compound containing half water hashigh fluidity, low hygroscopicity and impurity content, high thermodynamic stability and a wider application prospect.
Process for the preparation of 6-[D(-)alpha-(4-ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-alpha-phenylacetamido]-penicillanic acid and intermediates useful in this process
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, (2008/06/13)
The 6-[D(-)-alpha(4-ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-alphaphenylacetamido]penicillanic acid and the salts thereof are prepared by synthetizing the novel intermediates, thioesters of D(-)-alpha-(4-ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-alpha-phenylacetic acid, with mercaptoheterocycles and by converting them into the desired compound by reaction with 6-amino-penicillanic acid.
