5980-23-4

Basic information

• Product Name: 3,5-DICHLOROBENZAMIDE
• Synonyms: 3,5-DICHLOROBENZAMIDE;3,5-DICHLOROBENZAMIDE 99%
• CAS NO: 5980-23-4
• Molecular Formula: C₇H₅Cl₂NO
• Molecular Weight: 190.03
• Product Categories: Anilines, Amides & Amines;Chlorine Compounds
• Mol File: 5980-23-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 160 °C
• Boiling Point: 264.2 °C at 760 mmHg
• Flash Point: 113.6 °C
• Appearance: /
• Density: 1.439 g/cm³
• Vapor Pressure: 0.00984mmHg at 25°C
• Refractive Index: 1.596
• PKA: 14.82±0.50(Predicted)
• BRN: 2249768
• CAS DataBase Reference: 3,5-DICHLOROBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DICHLOROBENZAMIDE(5980-23-4)
• EPA Substance Registry System: 3,5-DICHLOROBENZAMIDE(5980-23-4)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• Hazardous Substances Data: 5980-23-4(Hazardous Substances Data)

Usage

General Description

3,5-Dichlorobenzamide is a chemical compound with the molecular formula C7H5Cl2NO. It is a white crystalline solid that is soluble in organic solvents and slightly soluble in water. 3,5-Dichlorobenzamide is primarily used as an intermediate in the production of pharmaceuticals and agricultural chemicals. It is also known to inhibit the growth of microorganisms, making it useful in the formulation of disinfectant and antimicrobial products. However, it is important to handle 3,5-Dichlorobenzamide with care as it is considered to be toxic if ingested or inhaled, and can cause skin and eye irritation upon contact. Overall, 3,5-Dichlorobenzamide is a versatile compound with various industrial applications and should be used with caution due to its potential hazards.

InChI:InChI=1/C7H5Cl2NO/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,(H2,10,11)

Upstream product

• 6575-00-4 3,5-dichlorobenzonitrile 
• 64-18-6 formic acid 
• 541-73-1 1,3-Dichlorobenzene 
• 100-51-6 benzyl alcohol 
• 60211-57-6 3,5-dichlorobenzyl alcohol 
• 51-36-5 3,5-dichlorobenzoic acid 

Downstream Products

• 626-43-7 3,5-Dichloroaniline 
• 104417-83-6 3,5-dichlorobenzoyl isocyanate 
• 403509-13-7 N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dichloropropyl]-3,5-dichlorobenzamide 
• 124808-45-3 (3,5-Dichloro-benzoyl)-carbamic acid (1R,3R,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester 
• 945257-74-9 3,5-dichloro-N-{4-[(5,5-dimethyl-2,4-dioxo-3-{4-[(trifluoro-methyl)thio]phenyl}imidazolidin-1-yl)methyl]pyridin-2-yl}benzamide 
• 25217-43-0 methyl (3,5-dichlorophenyl)carbamate 
• 53882-15-8 3,5-diaminobenzamide 

Relevant articles and documents

Visible light-mediated synthesis of amides from carboxylic acids and amine-boranes

Here, a photocatalytic deoxygenative amidation protocol using readily available amine-boranes and carboxylic acids is described. This approach features mild conditions, moderate-to-good yields, easy scale-up, and up to 62 examples of functionalized amides with diverse substituents. The synthetic robustness of this method was also demonstrated by its application in the late-stage functionalization of several pharmaceutical molecules.

Base-Mediated Amination of Alcohols Using Amidines

Novel and efficient base-mediated N-alkylation and amidation of amidines with alcohols have been developed, which can be carried out in one-pot reaction conditions, which allows for the synthesis of a wide range of N-alkyl amines and free amides in good to excellent yields with high atom economy. In contrast to borrowing hydrogen/hydrogen autotransfer or oxidative-type N-alkylation reactions, in which alcohols are activated by transition-metal-catalyzed or oxidative aerobic dehydrogenation, the use of amidines provides an effective surrogate of amines. This circumvents the inherent necessity in N-alkylation of an oxidant or a catalyst to be stabilized by ligands.

Tetrazole urease inhibitor type feed additive and preparation method thereof

The invention discloses a tetrazole urease inhibitor type feed additive and a preparation method thereof and belongs to the technical field of synthesis of feed additives. According to the technical scheme, a structural formula of the tetrazole urease inhibitor type feed additive is shown in the description. The invention further discloses the preparation method of the tetrazole urease inhibitor type feed additive. The tetrazole urease inhibitor type feed additive prepared by the preparation method can be used as non-protein nitrogen and has a certain inhibition effect on urease; the tetrazoleurease inhibitor type feed additive has the effects of sterilizing and resisting ulcer and has a potential of being used as an excellent animal feed additive.