59807-53-3

Basic information

• Product Name: 2-ADAMANTANYLETHYLAMINE
• Synonyms: 2-ADAMANTANYLETHYLAMINE;AKOS BC-1153;2-(2-Aminoethyl)adamantane;2-(Adamantan-2-yl)ethanamine;Tricyclo[3.3.1.1(3,7)]decane-2-ethanamine
• CAS NO: 59807-53-3
• Molecular Formula: C₁₂H₂₁N
• Molecular Weight: 179.3
• Product Categories: Adamantane derivatives
• Mol File: 59807-53-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 248.5±8.0℃ (760 Torr)
• Flash Point: 99.7±13.3℃
• Appearance: /
• Density: 0.992±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.0242mmHg at 25°C
• Refractive Index: 1.521
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-ADAMANTANYLETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ADAMANTANYLETHYLAMINE(59807-53-3)
• EPA Substance Registry System: 2-ADAMANTANYLETHYLAMINE(59807-53-3)

Safety Data

• Hazardous Substances Data: 59807-53-3(Hazardous Substances Data)

Usage

General Description

2-Adamantanylethylamine is a chemical compound also known as 1-(2-Adamantyl)ethylamine or AEA. It is a derivative of adamantane and belongs to the amphetamine class of compounds. AEA has been studied for its potential use as a stimulant and has been found to have affinity for the dopamine and serotonin receptors in the brain. It has been investigated for its potential use in the treatment of depression, attention deficit hyperactivity disorder (ADHD), and neurodegenerative diseases. However, its use is currently limited due to its potential for abuse and adverse side effects. Overall, 2-Adamantanylethylamine is a chemical compound with potential pharmacological applications but a need for further research and evaluation.

InChI:InChI=1/C12H21N/c13-2-1-12-10-4-8-3-9(6-10)7-11(12)5-8/h8-12H,1-7,13H2

Upstream product

• 38121-87-8 adamantan-2-ylacetonitrile 
• 700-58-3 2-Adamantanone 
• 38121-89-0 adamantan-2-ylideneacetonitrile 

Relevant articles and documents

Reduction of unsaturated adamantane-containing nitriles

The regularities of reduction of adamantane-containing unsaturated nitriles with Raney nickel were studied. It was shown that in the reaction conditions simultaneous reduction of both the double bond and the nitrile group occurs. The reduction of 2-(5-hydroxyadamant-2-ylidene)alkyl nitriles requires a longer time.

Colloid and nanosized catalysts in organic synthesis: XII. Hydrogenation of carbonitriles catalyzed by nickel nanoparticles

Hydrogenation of carbonitriles catalyzed by nickel nanoparticles in isopropanol proceeds under atmospheric pressure of hydrogen within 6-15 h to yield mainly secondary amines. Hydrogenation of α-aminonitriles results in reductive decyanation. β-Aminonitriles undergo hydrogenolysis at the nitrogen-carbon bond.

Condensation of adamantanone with methylene-active compounds

A convenient method was developed for the preparation of potentially bioactive substances with 2-adamantyl radical and of intermediates for their synthesis. Condensation of adamantanone with methylene-active compounds was performed, and the reaction features were determined.