59817-32-2Relevant articles and documents
Gasotransmitter Regulation of Phosphatase Activity in Live Cells Studied by Three-Channel Imaging Correlation
Ou, Pan,Zhang, Ruilong,Liu, Zhengjie,Tian, Xiaohe,Han, Guangmei,Liu, Bianhua,Hu, Zhangjun,Zhang, Zhongping
supporting information, p. 2261 - 2265 (2019/01/29)
Enzyme activity in live cells is dynamically regulated by small-molecule transmitters for maintaining normal physiological functions. A few probes have been devised to measure intracellular enzyme activities by fluorescent imaging, but the study of the re
N-(2-acetyl-4-morpholinophenyl amide derivatives for inducing differentiation of mesenchymal stem cells to endothelial cells
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Paragraph 0146-0153; 0166-0168, (2021/10/26)
The present invention refers to mesenchymal stem cells the vascular endothelial cells inducing their differentiation to the rarity piperidinyl/molpholine for containing amide derivatives and provides use thereof in medicaments. Said amide derivatives the middle ply treated with a vascular endothelial mesenchymal stem cells specifically cells differentiation induction, and are by using an balloon expansion alcoholic beverage like damage for vascular endothelial cells, such as by a vascular event for the effective treatment is enabled.
1-Substituted 4-(3-Hydroxyphenyl)piperazines are pure opioid receptor antagonists
Carroll, F. Ivy,Cueva, Juan Pablo,Thomas, James B.,Mascarella, S. Wayne,Runyon, Scott P.,Navarro, Hernan A.
scheme or table, p. 365 - 369 (2010/11/18)
This report describes the discovery that 1-substituted 4-(3-hydroxyphenyl) piperazines are pure opioid receptor antagonists. Compounds in this new series include N-phenylpropyl (3S)-3-methyl-4-(3-hydroxyphenyl)piperazine and (3R)-3-methyl-4-(3-hydroxyphenyl)piperazine, both of which display low nanomolar potencies at μ, δ, and κ receptors and pure antagonist properties in a [35S]GTPγS assay.