59830-61-4

Basic information

• Product Name: Carbamic acid, [(1S)-2,2-dimethoxy-1-(phenylmethyl)ethyl]-, phenylmethyl ester
• CAS NO: 59830-61-4
• Molecular Formula: C19H23NO4
• Molecular Weight: 329.396
• Mol File: 59830-61-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-2,2-dimethoxy-1-(phenylmethyl)ethyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-2,2-dimethoxy-1-(phenylmethyl)ethyl]-, phenylmethyl ester(59830-61-4)
• EPA Substance Registry System: Carbamic acid, [(1S)-2,2-dimethoxy-1-(phenylmethyl)ethyl]-, phenylmethyl ester(59830-61-4)

Safety Data

• Hazardous Substances Data: 59830-61-4(Hazardous Substances Data)

Upstream product

• 55707-43-2 1-benzyl-2,2-dimethoxyethylamine 
• 501-53-1 benzyl chloroformate 
• 6372-14-1 N-((benzyloxy)carbonyl)-L-phenylalaninol 
• 67-56-1 methanol 
• 59830-60-3 benzyl (1S)-(1-formyl-2-phenylethyl)carbamate 
• 100-46-9 benzylamine 
• 1084820-37-0 1,1-dimethoxy-3-phenylpropan-2-one oxime 
• 1217341-14-4 C₁₈H₂₃NO₂ 
• 89712-45-8 N,N-dimethylformamide dimethyl sulfate adduct 

Downstream Products

• 113283-64-0 ((S)-1-[1,3]Dioxan-2-yl-2-phenyl-ethyl)-carbamic acid benzyl ester 
• 59830-60-3 N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde 
• 6372-14-1 (2S)-2-(N-benzyloxycarbonyl)-amino-3-phenyl propanol 
• 1450733-52-4 (S)-1-benzyl-3-(1-benzyl-2-oxoethyl)-1-dimethylaminourea 
• 1450733-51-3 (S)-1,3-di(3-methoxybenzyl)-3-(1-benzyl-2,2-dimethoxyethyl)-1-piperidin-1-ylurea 
• 1450733-49-9 (S)-1,3-dibenzyl-3-(1-benzyl-2,2-dimethoxyethyl)-1-piperidin-1-ylurea 
• 1450733-43-3 (S)-1-benzyl-1-morpholino-3-(1-benzyl-2,2-dimethoxyethyl)urea 
• 1044510-14-6 (S)-1-benzyl-3-(1-benzyl-2,2-dimethoxyethyl)-1-piperidin-1-ylurea 
• 1450733-40-0 (S)-1-benzyl-3-(1-benzyl-2,2-dimethoxyethyl)-1-dimethylaminourea 
• 1450733-39-7 (S)-3-(1-benzyl-2,2-dimethoxyethyl)-1-piperidin-1-ylurea 
• 1044510-13-5 (S)-imidazole-1-carboxylic acid (1-benzyl-2,2-dimethoxyethyl)amide 
• 1450733-60-4 (S)-1,3-dibenzyl-1-(1-oxo-3-phenylpropan-2-yl)-3-(piperidin-1-yl)urea 
• 1450733-58-0 (S)-1-(3-hydroxybenzyl)-3-(1-benzyl-2-oxoethyl)-1-piperidin-1-ylurea 
• 1450733-55-7 (S)-1-benzyl-1-morpholino-3-(1-oxo-3-phenylpropan-2-yl)urea 

Relevant articles and documents

Modular construction of quaternary hemiaminal-based inhibitor candidates and their in cellulo assessment with HIV-1 protease

Non-peptidomimetic drug-like protease inhibitors have potential for circumventing drug resistance. We developed a much-improved synthetic route to our previously reported inhibitor candidate displaying an unusual quaternized hemi-aminal. This functional group forms from a linear precursor upon passage into physiological media. Seven variants were prepared and tested in cellulo with our HIV-1 fusion-protein technology that result in an eGFP-based fluorescent readout. Three candidates showed inhibition potency above 20 μM and toxicity at higher concentrations, making them attractive targets for further refinement. Importantly, our class of original inhibitor candidates is not recognized by two major multidrug resistance pumps, quite in contrast to most clinically applied HIV-1 protease inhibitors.

Diversity-oriented synthesis of a drug-like system displaying the distinctive N→C=O interaction

(Chemical Equation Presented) This study describes the syntheses and characterization of two hydrazino ureas. These fold into a six-membered ring by virtue of the infrequently observed δ+N→C=O δ- interaction when solvated by polar pr

Asymmetric Synthesis of 2- Amino Alcohol Derivatives from (S)-α-Amino Aldehydes via Acetal Templates

Titanium tetrachloride mediated addition of allyltrimethylsilane to chiral acetals derived from (S)-α-amino aldehydes and (+)-(2S,4S)-pentane-2,4-diol gave the anti-2-amino alcohol derivatives with considerably high diastereoselectivity.On the other hand,